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Project data set: Albers1   (1999)

Project Diet-induced changes in plasma phospholipid transfer protein activity, lipids, and lipoproteins in 15 inbred strains of mice

Plasma phospholipid transfer protein activity and lipoprotein phospholipid parameters were characterized at baseline and then again after 6 wks on high fat diet.

Study design: baseline and intervention; 1 cohort.
15 strains tested     female male     Test age: 6-14wks

Investigators Albers JJ, Paigen B   [Details, papers]

Protocol View phenotyping protocol and methods

Albers1
measurements



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blood — lipids         lipid profile  
Albers1
HDL cholesterol [mmol/L]     baseline and  high-fat diet 6wks
      • baseline   • after 6wks on diet   • Δchange    • comparison  
15 strains   age 6-8wks
                at baseline

  Inbred
Albers1
percentage of large HDL particles (10-13 nm) [%]     baseline and  high-fat diet 6wks
      • baseline   • after 6wks on diet   • Δchange    • comparison  
15 strains   age 6-8wks
                at baseline

  Inbred
Albers1
HDL peak size [nm]     baseline and  high-fat diet 6wks
      • baseline   • after 6wks on diet   • Δchange    • comparison  
15 strains   age 6-8wks
                at baseline

  Inbred
Albers1
non-HDL cholesterol [mmol/L]     baseline and  high-fat diet 6wks
      • baseline   • after 6wks on diet   • Δchange    • comparison  
15 strains   age 6-8wks
                at baseline

  Inbred
Albers1
total cholesterol [mmol/L]     baseline and  high-fat diet 6wks
      • baseline   • after 6wks on diet   • Δchange    • comparison  
15 strains   age 6-8wks
                at baseline

  Inbred
Albers1
total phospholipid [mmol/L]     baseline and  high-fat diet 6wks
      • baseline   • after 6wks on diet   • Δchange    • comparison  
15 strains   age 6-8wks
                at baseline

  Inbred
Albers1
HDL phospholipid [mmol/L]     baseline and  high-fat diet 6wks
      • baseline   • after 6wks on diet   • Δchange    • comparison  
15 strains   age 6-8wks
                at baseline

  Inbred
Albers1
non-HDL phospholipid [mmol/L]     baseline and  high-fat diet 6wks
      • baseline   • after 6wks on diet   • Δchange    • comparison  
15 strains   age 6-8wks
                at baseline

  Inbred
 
blood — lipids         radiolabeling  
Albers1
phospholipid transfer protein activity [µmol/mL/h]     baseline and  high-fat diet 6wks
      • baseline   • after 6wks on diet   • Δchange    • comparison  
15 strains   age 6-8wks
                at baseline

  Inbred
 
blood — lipids         lipid profile  
Albers1
triglycerides [mmol/L]     baseline and  high-fat diet 6wks
      • baseline   • after 6wks on diet   • Δchange    • comparison  
15 strains   age 6-8wks
                at baseline

  Inbred



Number of mice tested per strain, for each measurement

  
Changelog There have been no updates or corrections to the data set since MPD release in May 2003  
Reference
Albers JJ, Pitman W, Wolfbauer G, Cheung MC, Kennedy H, Tu AY, Marcovina SM, Paigen B. Relationship between phospholipid transfer protein activity and HDL level and size among inbred mouse strains. J Lipid Res. 1999 Feb;40(2):295-301.     PubMed 9925659     MGI

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Mice
Strain and animal info
Note
Some measurements were derived by MPD staff,
based on supplied data. [View list]

Albers1
downloads


Individual animal dataNot accessioned
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
No supplemental data for this project. 

 See also the MPD download center for more general data download options.





 




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