Paigen3: liver pathology images

Age 15-19 wks. Intervention: 8 wks on high-fat diet. Fasting conditions prior to sac.

These liver images are organized into two projects: Paigen1 (inbreds) and Paigen3 (obese mutants).

Microvacuoles are small vacuoles in hepatocyte cytoplasm, scored 1+ to 4+ in severity. Macrovacuoles are large single vacuoles that replace hepatocyte cytoplasm, scored 1+ to 4+ in severity. Inflammation refers to infiltrates of mixed inflammatory cells, including many neutrophils in liver scored 1+ to 4+ in severity.


Project: Paigen3


    Females   Males
Strain   Image link Scores (0-4)
• microvacuoles
• macrovacuoles
• inflammation 		  Image link Scores (0-4)
• microvacuoles
• macrovacuoles
• inflammation
B6(Cg)-Tubtub/J   Image 3   1   2   Image 3   0   1
B6.Cg-Ay/J   Image 3   0   2   Image 2   0   1
B6.Cg-Lepob/J   Image 4   3   0   Image 4   3   0
BKS.Cg-Dock7m +/+ Leprdb/J   Image 4   1   1   Image 4   0   0
BKSChpLt.HRS-Cpefat/J   Image 2   0   2   Image 3   0   2
C57BL/6J   Image 3   0   1   Image 3   0   3
C57BLKS/J   Image 2   0   2   Image 2   0   1