Age 15-19 wks. Intervention: 8 wks on high-fat diet. Fasting conditions prior to sac.
These liver images are organized into two projects:
Paigen1 (inbreds) and
Paigen3 (obese mutants).
Microvacuoles are small vacuoles in hepatocyte cytoplasm, scored 1+ to 4+ in severity.
Macrovacuoles are large single vacuoles that replace hepatocyte cytoplasm, scored 1+ to 4+ in severity.
Inflammation refers to infiltrates of mixed inflammatory cells, including many neutrophils in liver scored 1+ to 4+ in severity.