Paigen1: liver pathology images

Age 15-19 wks. Intervention: 8 wks on high-fat diet. Fasting conditions prior to sac.

These liver images are organized into two projects: Paigen1 (inbreds) and Paigen3 (obese mutants).

Microvacuoles are small vacuoles in hepatocyte cytoplasm, scored 1+ to 4+ in severity. Macrovacuoles are large single vacuoles that replace hepatocyte cytoplasm, scored 1+ to 4+ in severity. Inflammation refers to infiltrates of mixed inflammatory cells, including many neutrophils in liver scored 1+ to 4+ in severity.


Project: Paigen1


    Females   Males
Strain   Image link Scores (0-4)
• microvacuoles
• macrovacuoles
• inflammation 		  Image link Scores (0-4)
• microvacuoles
• macrovacuoles
• inflammation
129S1/SvImJ   Image 3   0   0   Image 3   0   0
A/J   Image 4   0   2   Image 4   0   3
AKR/J   Image 2   1   0   Image 3   1   0
BALB/cJ   Image 3   0   1   Image 3   0   0
BPH/2J   Image 3   0   0   Image 4   0   1
BPL/1J   Image 3   1   0   Image 2   2   0
BPN/3J   Image 2   0   0   Image 1   0   0
BTBR T+ tf/J   Image 1   0   0   Image 1   0   0
C3H/HeJ   Image 2   0   0   Image 3   0   0
C57BL/10J   Image 2   0   0   Image 3   0   1
C57BL/6J   Image 3   0   1   Image 3   0   3
C57BLKS/J   Image 2   0   2   Image 2   0   1
C57BR/cdJ   Image 2   0   0   Image 3   0   1
C57L/J   Image 2   0   0   Image 2   0   0
C58/J   Image 4   0   2   Image 4   0   4
CAST/EiJ   Image 3   0   0   Image 3   1   0
CBA/J   Image 3   1   0   Image 3   0   0
CE/J   Image 4   0   1   Image 4   0   1
CZECHII/EiJ   Image 0   2   0   Image 0   1   0
DBA/1J   Image 2   0   0   Image 1   0   1
DBA/2J   Image 3   0   0   Image 4   0   0
FVB/NJ   Image 4   0   1   Image 2   0   0
I/LnJ   Image 1   0   0   Image    
KK/HlJ   Image 2   2   1   Image 3   1   1
LP/J   Image 2   0   0   Image 2   1   0
MOLF/EiJ   Image 4   1   0   Image    
NOD/ShiLtJ   Image 3   0   1   Image 3   0   1
NON/ShiLtJ   Image 3   0   2   Image 3   0   3
NZB/BlNJ   Image 3   0   2   Image 3   0   3
NZW/LacJ   Image 4   0   0   Image 3   0   0
P/J   Image 3   1   0   Image 3   1   0
PERA/EiJ   Image 4   0   0   Image    
PL/J   Image 3   0   1   Image 2   2   1
RBF/DnJ   Image 4   0   0   Image 4   0   0
RF/J   Image 4   0   0   Image 3   2   0
RIIIS/J   Image 4   0   1   Image 4   1   1
SEA/GnJ   Image 2   0   0   Image 2   0   0
SJL/J   Image 3   0   0   Image 3   0   2
SM/J   Image 2   0   1   Image 1   0   2
SPRET/EiJ   Image 0   0   0   Image 0   0   0
SWR/J   Image 4   0   3   Image 1   0   3
WSB/EiJ   Image 3   0   0   Image 1   0   0
YBR/EiJ   Image 3   0   3   Image