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Intervention studies

Studies where a foreign substance or pathogen was administered, or an environmental perturbation was introduced and compared against a control cohort or baseline readings. Click below to arrive at available MPD data and Wikipedia linkouts. The rightmost column below indicates available data types.

The list below includes these sections:     • diets     • drugs and alcohol     • exercise     • pathogens / parasites     • toxicity / challenges / mutagens
 
diets
  high-fat diet   diet high in fat pheno, QTL, expr
  high-fat diet and ethanol   effect on liver of fat and ethanol together pheno
  high-fat high-sucrose diet   effect on liver of fat and sucrose together pheno
  macronutrient diet option   macronutrient diet option QTL
  restricted diet   reduced food amount pheno
  salt (NaCl)   table salt NaCl pheno, QTL
  sucrose   table sugar pheno
  western diet   diet with typical Western characteristics QTL
 
drugs and alcohol
  acetaminophen   pain reliever e.g. Tylenol pheno
  atenolol   treatment for cardiovascular disorders pheno
  captopril   antihypertensive agent, hyperglycemia study misc
  cocaine   psychostimulant pheno, QTL
  cyclophosphamide   alkylating agent, lupus erythematosus study misc
  DB289   antiparasitic pheno
  diazepam   anxiety reliever e.g. Valium pheno
  docetaxel   anti-mitotic chemotherapy medication, cancer study misc
  ethanol   alcohol EtOH pheno, QTL
  ethanol and high-fat diet   effect on liver of fat and ethanol together pheno
  fluoxetine   antidepressant e.g. Prozac pheno
  glatiramer acetate   immunosuppressive agent, inflammatory bowel disease study misc
  haloperidol   antipsychotic pheno
  imipramine   antidepressant pheno
  isoniazid   treatment for tuberculosis pheno
  isoproterenol   treatment for cardiovascular disorders pheno
  lamotrigine   anticonvulsant pheno
  L-DOPA   dopamine agent, Parkinson's Disease study misc
  lithium   mood stabilizer pheno
  metformin   hypoglycemic agent, diabetes study misc
  methamphetamine   psychostimulant pheno
  nicotine   component of tobacco smoke pheno
  olanzapine   treatment for schizophrenia and bipolar pheno
  paclitaxel   anti-mitotic chemotherapy medication, cancer study misc
  pilocarpine   convulsant pheno
  quinelorane   dopamine agonist pheno
  R-6-Br-APB   dopamine agonist pheno
  rosiglitazone   hypoglycemic agent, diabetes and obesity studies misc
  salbutamol   bronchodilator agent, asthma studies misc
 
exercise
  exercise   option/availability of running wheel pheno
 
pathogens / parasites
  Bacillus anthracis lethal toxin   anthrax pheno
  Candida albicans   fungal infection pheno
  F.nucleatum   periodontal pathogenic bacteria pheno
  influenza A (H1N1) virus   viral infection pheno
  influenza A (H5N1) virus   viral infection pheno
  P.gingivalis   periodontal pathogenic bacteria pheno
  Plasmodium berghei   malaria pheno
  Plasmodium chabaudi   malaria pheno
  Staphylococcus aureus   bacterial infection pheno
  Streptococcus zooepidemicus   respiratory challenge study misc
 
toxicity / challenges / mutagens
  cadmium   toxicity pheno
  ENU   ethylnitrosourea, mutagen pheno
  lipopolysaccharide   (LPS) endotoxin, respiratory challenge expr, misc
  methacholine   bronchoconstrictor, respiratory tests pheno, QTL
  ovalbumin   allergen, repiratory challenge pheno
  OxPAPC   TLR signalling inhibitor expr
  ozone   air pollutant, respiratory challenge misc
  radiation   ionizing radiation pheno
  trichloroethylene   (TCE) industrial contaminant pheno, expr
  UV radiation   ultraviolet radiation QTL


 




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