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Measurement context
This strain survey phenotype measurement is from:
Frankel1
Frankel WN, White HS – Drug study: Induced seizures and their suppression with lamotrigine in 16 inbred strains of mice
Measurement:
brain — electroconvulsive threshold
pulse generator
Frankel1
median critical current (CC
50
) for maximal tonic hindlimb extension seizure, frontal stimulation (at BH)
[mA]
4
strains
age
6-11wks
Inbred
Ontology codings:
VT:0015058 – brain physiology trait
MP:0002194 – maximal tonic hindlimb extension seizures
MA:0000168 – brain
Measurement is a member of this set:
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brain — electroconvulsive threshold
pulse generator
Frankel1
critical current required for 50% of mice (CC
50
) to reach maximal tonic hindlimb seizure [mA]
electrode placement:
• frontal (BH)
• transcorneal (BH)
• transcorneal (SL)
• comparison
16
strains
age
6-11wks
Inbred