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Measurement context
This strain survey phenotype measurement is from:
Threadgill2
Threadgill DW, Harrill A – Drug study: Acetaminophen pharmakokinetics and drug-induced liver injury in males of 5 inbred strains of mice
Measurement:
blood — xenobiotics — drug and metabolite concentration
HPLC
Threadgill2
acetaminophen concentration (serum APAP), t=0.5h
[µg/mL]
acetaminophen
50mg/kg
5
strains
age
6-8wks
Inbred
Ontology codings:
VT:0002121 – metabolism trait
VT:0010487 – response to xenobiotic stimulus trait
MP:0008875 – abnormal xenobiotic pharmacokinetics
MA:0002502 – serum
Measurement is a member of this set:
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blood — xenobiotics — drug and metabolite concentration
HPLC
Threadgill2
serum acetominophen (APAP) [µg/mL]
baseline and
acetaminophen
50mg/kg
• baseline
• 0.5h
• 1h
• 2h
• 3h
• 6h
• time comparison
5
strains
age
6-8wks
Inbred