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MPD - Phenotype data: SHIRPA
behavior methodologies
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SHIRPA assessment (SHIRPA)
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•Inbred only
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appearance and coat color
SHIRPA
Jaxpheno7
body presentation [score]
• body position
• pelvic elevation
• tail elevation
• hindlimb splay
• limb pattern
6
strains
age
10wks
Inbred
Jaxpheno7
color evaluation of plantar surface and forelimb digits
during supine restraint (score 0-2)
[score]
6
strains
age
10wks
Inbred
Lake2
body presentation [score]
• pelvic elevation
• tail elevation
• body position
• hindlimb splay
23
strains
age
8wks
B6.A consomic
Lake2
color evaluation of plantar surface and forelimb digits
during supine restraint (score 0-2)
[score]
23
strains
age
8wks
B6.A consomic
behavior — anxiety
SHIRPA
Jaxpheno7
degree of behavioral inhibition or arousal [score]
• transfer arousal
• freezing
6
strains
age
10wks
Inbred
Jaxpheno7
frequency of behavioral displacement (jar) [n]
• defecation
• urination
6
strains
age
10wks
Inbred
Jaxpheno7
frequency of behavioral displacement (arena) [n]
• defecation
• urination
6
strains
age
10wks
Inbred
Lake2
frequency of behavioral displacement [n]
• defecation
• urination
23
strains
age
8wks
B6.A consomic
Lake2
degree of behavioral inhibition or arousal [score]
• transfer arousal
• freezing
23
strains
age
8wks
B6.A consomic
Lake2
frequency of behavioral displacement [n]
• defecation
• urination
23
strains
age
8wks
B6.A consomic
behavior — involuntary movement
SHIRPA
Jaxpheno7
constant trembling in view-jar (score 0-2)
[score]
6
strains
age
10wks
Inbred
Jaxpheno7
short sporadic twitches in view-jar (score 0-2)
[score]
6
strains
age
10wks
Inbred
Lake2
constant trembling in view-jar (score 0-2)
[score]
23
strains
age
8wks
B6.A consomic
Lake2
short sporadic twitches in view-jar (score 0-2)
[score]
23
strains
age
8wks
B6.A consomic
behavior — locomotor activity
SHIRPA
Jaxpheno7
spontaneous activity level in view-jar (score 0-3)
[score]
6
strains
age
10wks
Inbred
Lake2
spontaneous activity level in view-jar (score 0-3)
[score]
23
strains
age
8wks
B6.A consomic
behavior — wildness
SHIRPA
Jaxpheno7
aggressive behavior [score]
• provoked biting
• irritability
• aggression
• vocalization
• finger approach
6
strains
age
10wks
Inbred
Lake2
aggressive behavior [score]
• provoked biting
• irritability
• aggression
• vocalization
23
strains
age
8wks
B6.A consomic
nervous system — autonomic function
SHIRPA
Jaxpheno7
autonomic function [score]
• palpebral closing
• piloerection
• airpuff startle reflex
• trunk curl
• hindlimb grasp
• lacrimal reflex
• salivary reflex
6
strains
age
10wks
Inbred
Lake2
autonomic function [score]
• palpebral closing
• piloerection
• airpuff startle reflex
• trunk curl
• hindlimb grasp
• lacrimal reflex
• salivary reflex
23
strains
age
8wks
B6.A consomic
nervous system — neuromuscular function
SHIRPA
Jaxpheno7
muscle function and fitness [score]
• gait
• positional passivity
• body tone
• limb tone
• abdominal tone
6
strains
age
10wks
Inbred
Lake2
muscle function and fitness [score]
• gait
• positional passivity
• body tone
• limb tone
• abdominal tone
• response to tail suspension
• response to rotation
23
strains
age
8wks
B6.A consomic
nervous system — sensorimotor function
SHIRPA
Jaxpheno7
motor responses to sensory stimulus [score]
• touch escape
• visual placing
• pinna reflex
• corneal reflex
• hindfoot withdrawal reflex
• cross extensor reflex
• wire grip maneuver
• righting reflex
• catalepsy
• negative geotaxis
6
strains
age
10wks
Inbred
Lake2
motor responses to sensory stimulus [score]
• touch escape
• visual placing
• pinna (ear) reflex
• corneal reflex
• hindfoot withdrawal reflex
• cross extensor reflex
• righting reflex
• catalepsy
• negative geotaxis
23
strains
age
8wks
B6.A consomic
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