Home       About             Help       Phenotype data > DBA/2J strain > interventions > trichloroethylene (industrial contaminant)   See also:   Wikipedia Measurements: About these DBA/2J averages (♀ ♂) Exit DBA/2J mode blood — clinical chemistry — enzymes — ALT         metabolic panel   Rusyn2 alanine aminotransferase (serum ALT) [IU/L]     control and  trichloroethylene       control group:             • 2h  ...... 43.9 (N=3)               • 8h  ...... 35.2 (N=3)               • 24h  ...... 29.2 (N=3)                 • time comparison         treated group:             • 2h  ...... 30.0 (N=3)               • 8h  ...... 45.1 (N=3)               • 24h  ...... 23.6 (N=3)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 ALT, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred   blood — clinical chemistry — enzymes — AST         metabolic panel   Rusyn2 aspartate aminotransferase (serum AST) [IU/L]     control and  trichloroethylene       control group:             • 2h  ...... 179 (N=3)               • 8h  ...... 138 (N=3)               • 24h  ...... 142 (N=2)                 • time comparison         treated group:             • 2h  ...... 139 (N=3)               • 8h  ...... 118 (N=3)               • 24h  ...... 110 (N=3)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 AST, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred   blood — clinical chemistry — urea nitrogen         metabolic panel   Rusyn2 blood urea nitrogen (serum BUN) [mg/dL]     control and  trichloroethylene       control group:             • 2h  ...... 17.7 (N=3)               • 8h  ...... 23.3 (N=3)               • 24h  ...... 13.7 (N=3) ▼                 • time comparison         treated group:             • 2h  ...... 15.3 (N=3) ▼               • 8h  ...... 16.7 (N=3)               • 24h  ...... 10.0 (N=3) ▼                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 blood urea nitrogen (BUN), control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred   blood — xenobiotics — drug and metabolite concentration         HPLC   Rusyn2 dichloroacetic acid (serum DCA x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ...... 0 (N=3) ▼               • 8h  ...... 60.0 (N=3)               • 24h  ...... 10.0 (N=2)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 trichloroacetic acid (serum TCA) [nmol/mL]   trichloroethylene         treated group:             • 2h  ...... 257 (N=3)               • 8h  ...... 1061 (N=3)               • 24h  ...... 208 (N=2)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 DCV cysteine (serum DCVC x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ...... 0.977 (N=2)               • 8h  ...... 0.853 (N=3)               • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 DCV glutathione (serum DCVG x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ...... 8.98 (N=3)               • 8h  ...... 0.0712 (N=3)               • 24h  ...... 0.149 (N=1)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 above metabolites compared   trichloroethylene         treated group:             2h              8h              24h              17 strains   age 7wks   Inbred   local experiment parameter   Rusyn2 body weight [g]     control and  trichloroethylene       control group:             • 2h  ...... 14.3 (N=3) ▼               • 8h  ...... 18.6 (N=3)               • 24h  ...... 18.9 (N=3)                 • time comparison         treated group:             • 2h  ...... 16.9 (N=3)               • 8h  ...... 19.9 (N=3)               • 24h  ...... 19.2 (N=3)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 body weight, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred Rusyn2 liver weight as a percentage of body weight [ratio]     control and  trichloroethylene       control group:             • 2h  ...... 9.33 (N=3) ▲▲               • 8h  ...... 4.30 (N=3)               • 24h  ...... 5.30 (N=3)                 • time comparison         treated group:             • 2h  ...... 8.10 (N=3) ▲▲               • 8h  ...... 4.67 (N=3)               • 24h  ...... 5.40 (N=3)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 adjusted liver weight, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred

Video tutorial session 2 explains the use of this page.

Hosted by:

Contact us About MPD Also at JAX

Units Changelog Downloads

Citing Funding Terms of Use