Home       About             Help       Phenotype data > WSB/EiJ strain > interventions > trichloroethylene (industrial contaminant)   See also:   Wikipedia Measurements: About these WSB/EiJ averages (♀ ♂) Exit WSB/EiJ mode blood — clinical chemistry — enzymes — ALT         metabolic panel   Rusyn2 alanine aminotransferase (serum ALT) [IU/L]     control and  trichloroethylene       control group:             • 2h  ......             • 8h  ...... 95.1 (N=1) ▲▲               • 24h  ......               • time comparison         treated group:             • 2h  ......             • 8h  ...... 156 (N=3) ▲▲               • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 ALT, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred   blood — clinical chemistry — enzymes — AST         metabolic panel   Rusyn2 aspartate aminotransferase (serum AST) [IU/L]     control and  trichloroethylene       control group:             • 2h  ......             • 8h  ...... 220 (N=1) ▲               • 24h  ......               • time comparison         treated group:             • 2h  ......             • 8h  ...... 323 (N=3) ▲               • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 AST, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred   blood — clinical chemistry — urea nitrogen         metabolic panel   Rusyn2 blood urea nitrogen (serum BUN) [mg/dL]     control and  trichloroethylene       control group:             • 2h  ......             • 8h  ...... 24.0 (N=1)               • 24h  ......               • time comparison         treated group:             • 2h  ......             • 8h  ...... 37.7 (N=3) ▲▲               • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 blood urea nitrogen (BUN), control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred   blood — xenobiotics — drug and metabolite concentration         HPLC   Rusyn2 dichloroacetic acid (serum DCA x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ......             • 8h  ......             • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 trichloroacetic acid (serum TCA) [nmol/mL]   trichloroethylene         treated group:             • 2h  ......             • 8h  ......             • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 DCV cysteine (serum DCVC x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ......             • 8h  ...... 0.717 (N=3)               • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 DCV glutathione (serum DCVG x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ......             • 8h  ...... 2.28 (N=3)               • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 above metabolites compared   trichloroethylene         treated group:             2h              8h              24h              17 strains   age 7wks   Inbred   local experiment parameter   Rusyn2 body weight [g]     control and  trichloroethylene       control group:             • 2h  ......             • 8h  ...... 15.3 (N=1) ▼               • 24h  ......               • time comparison         treated group:             • 2h  ......             • 8h  ...... 14.3 (N=3) ▼               • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 body weight, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred Rusyn2 liver weight as a percentage of body weight [ratio]     control and  trichloroethylene       control group:             • 2h  ......             • 8h  ...... 3.90 (N=1) ▼               • 24h  ......               • time comparison         treated group:             • 2h  ......             • 8h  ...... 3.97 (N=3)               • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 adjusted liver weight, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred

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