Home       About             Help       Phenotype data > AKR/J strain > interventions > trichloroethylene (industrial contaminant)   See also:   Wikipedia Measurements: About these AKR/J averages (♀ ♂) Exit AKR/J mode blood — clinical chemistry — enzymes — ALT         metabolic panel   Rusyn2 alanine aminotransferase (serum ALT) [IU/L]     control and  trichloroethylene       control group:             • 2h  ...... 38.8 (N=3)               • 8h  ...... 33.9 (N=3)               • 24h  ...... 15.2 (N=3) ▼                 • time comparison         treated group:             • 2h  ...... 56.4 (N=3)               • 8h  ...... 73.5 (N=3)               • 24h  ...... 11.9 (N=3) ▼                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 ALT, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred   blood — clinical chemistry — enzymes — AST         metabolic panel   Rusyn2 aspartate aminotransferase (serum AST) [IU/L]     control and  trichloroethylene       control group:             • 2h  ...... 114 (N=3)               • 8h  ...... 111 (N=3)               • 24h  ...... 78.3 (N=3)                 • time comparison         treated group:             • 2h  ...... 177 (N=3)               • 8h  ...... 204 (N=3)               • 24h  ...... 82.3 (N=3) ▼                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 AST, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred   blood — clinical chemistry — urea nitrogen         metabolic panel   Rusyn2 blood urea nitrogen (serum BUN) [mg/dL]     control and  trichloroethylene       control group:             • 2h  ...... 19.3 (N=3)               • 8h  ...... 20.0 (N=3)               • 24h  ...... 16.0 (N=3)                 • time comparison         treated group:             • 2h  ...... 17.0 (N=3)               • 8h  ...... 18.0 (N=3)               • 24h  ...... 16.0 (N=3)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 blood urea nitrogen (BUN), control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred   blood — xenobiotics — drug and metabolite concentration         HPLC   Rusyn2 dichloroacetic acid (serum DCA x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ......             • 8h  ......             • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 trichloroacetic acid (serum TCA) [nmol/mL]   trichloroethylene         treated group:             • 2h  ......             • 8h  ......             • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 DCV cysteine (serum DCVC x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ......             • 8h  ......             • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 DCV glutathione (serum DCVG x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ......             • 8h  ...... 0.313 (N=2)               • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 above metabolites compared   trichloroethylene         treated group:             2h              8h              24h              17 strains   age 7wks   Inbred   local experiment parameter   Rusyn2 body weight [g]     control and  trichloroethylene       control group:             • 2h  ...... 24.4 (N=3)               • 8h  ...... 25.6 (N=3)               • 24h  ...... 26.6 (N=3) ▲                 • time comparison         treated group:             • 2h  ...... 24.8 (N=3)               • 8h  ...... 24.3 (N=3)               • 24h  ...... 24.9 (N=3)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 body weight, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred Rusyn2 liver weight as a percentage of body weight [ratio]     control and  trichloroethylene       control group:             • 2h  ...... 4.93 (N=3)               • 8h  ...... 5.60 (N=3) ▲               • 24h  ...... 5.63 (N=3)                 • time comparison         treated group:             • 2h  ...... 5.27 (N=3)               • 8h  ...... 4.90 (N=3)               • 24h  ...... 5.63 (N=3)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 adjusted liver weight, control vs. treated   trichloroethylene         2h        8h        24h        17 strains   age 7wks   Inbred

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