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Phenotype data > MPD - Phenotype data: trichloroethylene interventions >
trichloroethylene
((TCE) industrial contaminant)
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blood — clinical chemistry — enzymes — ALT         metabolic panel  
Rusyn2
alanine aminotransferase (serum ALT) [IU/L]     control and  trichloroethylene      
  control group:    • 2h    • 8h    • 24h    • time comparison        
  treated group:    • 2h    • 8h    • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
ALT, control vs. treated   trichloroethylene      
2h  8h  24h 
17 strains   age 7wks
  Inbred
 
blood — clinical chemistry — enzymes — AST         metabolic panel  
Rusyn2
aspartate aminotransferase (serum AST) [IU/L]     control and  trichloroethylene      
  control group:    • 2h    • 8h    • 24h    • time comparison        
  treated group:    • 2h    • 8h    • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
AST, control vs. treated   trichloroethylene      
2h  8h  24h 
17 strains   age 7wks
  Inbred
 
blood — clinical chemistry — urea nitrogen         metabolic panel  
Rusyn2
blood urea nitrogen (serum BUN) [mg/dL]     control and  trichloroethylene      
  control group:    • 2h    • 8h    • 24h    • time comparison        
  treated group:    • 2h    • 8h    • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
blood urea nitrogen (BUN), control vs. treated   trichloroethylene      
2h  8h  24h 
17 strains   age 7wks
  Inbred
 
blood — xenobiotics — drug and metabolite concentration         HPLC  
Rusyn2
dichloroacetic acid (serum DCA x 10-3) [nmol/mL]   trichloroethylene      
treated group:  • 2h  • 8h  • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
trichloroacetic acid (serum TCA) [nmol/mL]   trichloroethylene      
treated group:  • 2h  • 8h  • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
DCV cysteine (serum DCVC x 10-3) [nmol/mL]   trichloroethylene      
treated group:  • 2h  • 8h  • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
DCV glutathione (serum DCVG x 10-3) [nmol/mL]   trichloroethylene      
treated group:  • 2h  • 8h  • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
above metabolites compared   trichloroethylene      
treated group:  2h  8h  24h 
17 strains   age 7wks
  Inbred
 
local experiment parameter  
Rusyn2
body weight [g]     control and  trichloroethylene      
  control group:    • 2h    • 8h    • 24h    • time comparison        
  treated group:    • 2h    • 8h    • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
body weight, control vs. treated   trichloroethylene      
2h  8h  24h 
17 strains   age 7wks
  Inbred
Rusyn2
liver weight as a percentage of body weight [ratio]     control and  trichloroethylene      
  control group:    • 2h    • 8h    • 24h    • time comparison        
  treated group:    • 2h    • 8h    • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
adjusted liver weight, control vs. treated   trichloroethylene      
2h  8h  24h 
17 strains   age 7wks
  Inbred


 


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