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C57BL/6J strain > interventions
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MPD - Phenotype data: lithium
lithium
(mood stabilizer)
See also:
Wikipedia
Measurements:
About these
C57BL/6J
averages
(
♀
♂
)
Exit
C57BL/6J
mode
behavior — stress reactivity
forced swim test
Gould1
duration of immobility [s]
control and
lithium
lithium dose [mg/kg]:
• 0(saline)
......
212
▲
• 200
......
188
▲
• 300
......
187
▲
• 400
......
192
▲
• comparison
11
strains
age
7-8wks
Inbred
blood — xenobiotics — drug and metabolite concentration
flame photometry
Gould1
serum lithium concentration [mmol/L]
lithium
lithium dose [mg/kg]:
• 200
......
0.641
• 300
......
1.09
• 400
......
1.33
▼
• comparison
11
strains
age
7-8wks
Inbred
brain — xenobiotics — drug and metabolite concentration
flame photometry
Gould1
brain lithium concentration [mmol/L]
lithium
lithium dose [mg/kg]:
• 200
......
0.840
• 300
......
1.38
• 400
......
1.55
▼
• comparison
11
strains
age
7-8wks
Inbred
drug effect profile
flame photometry
Gould1
drug effect profile
lithium
lithium dose [mg/kg]:
200
300
400
11
strains
age
7-8wks
Inbred
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