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Phenotype data > C57BL/6J strain > interventions >
MPD - Phenotype data: lithium
lithium
(mood stabilizer)
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C57BL/6J
averages
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behavior — stress reactivity         forced swim test  
Gould1
duration of immobility [s]     control and  lithium
      lithium dose [mg/kg]:
            • 0(saline)  ...... 212  
            • 200  ...... 188  
            • 300  ...... 187  
            • 400  ...... 192  
              • comparison  
11 strains   age 7-8wks
  Inbred
 
blood — xenobiotics — drug and metabolite concentration         flame photometry  
Gould1
serum lithium concentration [mmol/L]   lithium
      lithium dose [mg/kg]:
            • 200  ...... 0.641  
            • 300  ...... 1.09  
            • 400  ...... 1.33  
              • comparison  
11 strains   age 7-8wks
  Inbred
 
brain — xenobiotics — drug and metabolite concentration         flame photometry  
Gould1
brain lithium concentration [mmol/L]   lithium
      lithium dose [mg/kg]:
            • 200  ...... 0.840  
            • 300  ...... 1.38  
            • 400  ...... 1.55  
              • comparison  
11 strains   age 7-8wks
  Inbred
 
drug effect profile         flame photometry  
Gould1
drug effect profile   lithium
      lithium dose [mg/kg]:
            200 
            300 
            400 
           
11 strains   age 7-8wks
  Inbred


 


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