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C57BL/6J strain > interventions
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MPD - Phenotype data: haloperidol
haloperidol
(antipsychotic)
See also:
Wikipedia
Measurements:
About these
C57BL/6J
averages
(
♀
♂
)
Exit
C57BL/6J
mode
behavior — balance and coordination
inclined screen test
Crowley1
extrapyramidal side effects (EPS) [s]
baseline and
haloperidol
day:
• 0
......
3.20
• 3
......
7.00
• 7
......
4.40
• 30
......
5.40
• 60
......
6.40
• 120
......
5.40
• time comparison
27
strains
age
9-28wks
Inbred
behavior — exploratory
open field test
Crowley1
center occupancy [%]
baseline and
haloperidol
day:
• 0
......
10.8
▲
• 30
......
3.90
• 60
......
3.41
• 120
......
10.7
▲
• time comparison
27
strains
age
9-28wks
Inbred
behavior — involuntary movement
observation
Crowley1
tongue protrusion [n]
baseline and
haloperidol
day:
• 0
......
0.200
• 30
......
1.60
• 60
......
2.20
• 120
......
4.60
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
overt chewing movement [n]
baseline and
haloperidol
day:
• 0
......
18.4
• 30
......
87.8
▲
• 60
......
41.0
• 120
......
74.0
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
subtle chewing movement [n]
baseline and
haloperidol
day:
• 0
......
56.0
• 30
......
112
• 60
......
79.2
• 120
......
40.6
▼
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
jaw tremor [s]
baseline and
haloperidol
day:
• 0
......
11.0
• 30
......
15.6
• 60
......
26.6
• 120
......
22.2
• time comparison
27
strains
age
9-28wks
Inbred
behavior — involuntary movement
open field test
Crowley1
repetitive behavior (stereotypy) [n]
baseline and
haloperidol
day:
• 0
......
7377
▲
• 30
......
3617
• 60
......
3188
• 120
......
5140
• time comparison
27
strains
age
9-28wks
Inbred
behavior — locomotor activity
open field test
Crowley1
distance traveled [cm]
baseline and
haloperidol
day:
• 0
......
7370
• 30
......
2400
• 60
......
2385
• 120
......
4246
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
vertical activity [n]
baseline and
haloperidol
day:
• 0
......
1035
▲
• 30
......
240
• 60
......
223
• 120
......
552
• time comparison
27
strains
age
9-28wks
Inbred
blood — xenobiotics — drug and metabolite concentration
mass spectrometry
Crowley1
plasma haloperidol concentration [nM]
haloperidol
day:
• 30
......
12.0
▼
• 60
......
10.5
▼
• 90
......
5.52
▼
• 120
......
3.44
▼
• time comparison
27
strains
age
9-28wks
Inbred
body weight
scales
Crowley1
body weight [g]
baseline and
haloperidol
• starting
......
26.4
• ending
......
31.5
• time comparison
27
strains
age
9-28wks
Inbred
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