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AKR/J strain > interventions
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MPD - Phenotype data: haloperidol
haloperidol
(antipsychotic)
See also:
Wikipedia
Measurements:
About these
AKR/J
averages
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)
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AKR/J
mode
behavior — balance and coordination
inclined screen test
Crowley1
extrapyramidal side effects (EPS) [s]
baseline and
haloperidol
day:
• 0
......
3.40
▲
• 3
......
114
• 7
......
89.6
• 30
......
28.0
• 60
......
20.4
• 120
......
22.6
• time comparison
27
strains
age
9-28wks
Inbred
behavior — exploratory
open field test
Crowley1
center occupancy [%]
baseline and
haloperidol
day:
• 0
......
6.94
• 30
......
4.29
• 60
......
1.84
• 120
......
4.96
• time comparison
27
strains
age
9-28wks
Inbred
behavior — involuntary movement
observation
Crowley1
tongue protrusion [n]
baseline and
haloperidol
day:
• 0
......
0.200
• 30
......
4.40
• 60
......
4.20
• 120
......
6.80
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
overt chewing movement [n]
baseline and
haloperidol
day:
• 0
......
21.2
• 30
......
54.4
• 60
......
57.8
• 120
......
80.2
▲
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
subtle chewing movement [n]
baseline and
haloperidol
day:
• 0
......
57.4
• 30
......
62.2
• 60
......
53.8
• 120
......
52.6
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
jaw tremor [s]
baseline and
haloperidol
day:
• 0
......
0.400
• 30
......
3.00
▼
• 60
......
0.200
▼
• 120
......
6.60
• time comparison
27
strains
age
9-28wks
Inbred
behavior — involuntary movement
open field test
Crowley1
repetitive behavior (stereotypy) [n]
baseline and
haloperidol
day:
• 0
......
5481
• 30
......
2773
• 60
......
2624
• 120
......
4483
• time comparison
27
strains
age
9-28wks
Inbred
behavior — locomotor activity
open field test
Crowley1
distance traveled [cm]
baseline and
haloperidol
day:
• 0
......
7497
• 30
......
2786
• 60
......
2800
• 120
......
6146
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
vertical activity [n]
baseline and
haloperidol
day:
• 0
......
238
• 30
......
92.6
• 60
......
74.2
• 120
......
167
• time comparison
27
strains
age
9-28wks
Inbred
blood — xenobiotics — drug and metabolite concentration
mass spectrometry
Crowley1
plasma haloperidol concentration [nM]
haloperidol
day:
• 30
......
12.7
▼
• 60
......
11.0
▼
• 90
......
4.62
▼
• 120
......
2.66
▼
• time comparison
27
strains
age
9-28wks
Inbred
body weight
scales
Crowley1
body weight [g]
baseline and
haloperidol
• starting
......
29.8
• ending
......
38.9
• time comparison
27
strains
age
9-28wks
Inbred
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