Home       About             Help       Phenotype data > NOD/ShiLtJ strain > interventions > haloperidol (antipsychotic)   See also:   Wikipedia Measurements: About these NOD/ShiLtJ averages (♀ ♂) Exit NOD/ShiLtJ mode behavior — balance and coordination         inclined screen test   Crowley1 extrapyramidal side effects (EPS) [s]     baseline and  haloperidol       day:             • 0  ...... 2.60               • 3  ...... 2.80               • 7  ...... 8.20               • 30  ...... 5.40               • 60  ...... 4.00               • 120  ...... 5.20                 • time comparison   27 strains   age 9-28wks   Inbred   behavior — exploratory         open field test   Crowley1 center occupancy [%]     baseline and  haloperidol       day:             • 0  ...... 13.2 ▲               • 30  ...... 15.5 ▲               • 60  ...... 14.3 ▲               • 120  ...... 16.1 ▲▲                 • time comparison   27 strains   age 9-28wks   Inbred   behavior — involuntary movement         observation   Crowley1 tongue protrusion [n]     baseline and  haloperidol       day:             • 0  ...... 0.600               • 30  ...... 8.40               • 60  ...... 3.80               • 120  ...... 8.20                 • time comparison   27 strains   age 9-28wks   Inbred Crowley1 overt chewing movement [n]     baseline and  haloperidol       day:             • 0  ...... 4.40               • 30  ...... 47.0               • 60  ...... 19.6               • 120  ...... 18.6                 • time comparison   27 strains   age 9-28wks   Inbred Crowley1 subtle chewing movement [n]     baseline and  haloperidol       day:             • 0  ...... 34.0               • 30  ...... 107               • 60  ...... 53.6               • 120  ...... 37.4 ▼                 • time comparison   27 strains   age 9-28wks   Inbred Crowley1 jaw tremor [s]     baseline and  haloperidol       day:             • 0  ...... 9.20               • 30  ...... 13.0               • 60  ...... 6.00               • 120  ...... 12.4                 • time comparison   27 strains   age 9-28wks   Inbred   behavior — involuntary movement         open field test   Crowley1 repetitive behavior (stereotypy) [n]     baseline and  haloperidol       day:             • 0  ...... 7107 ▲               • 30  ...... 5727 ▲               • 60  ...... 5751 ▲               • 120  ...... 6243 ▲                 • time comparison   27 strains   age 9-28wks   Inbred   behavior — locomotor activity         open field test   Crowley1 distance traveled [cm]     baseline and  haloperidol       day:             • 0  ...... 7971               • 30  ...... 6756 ▲               • 60  ...... 6560 ▲               • 120  ...... 8377 ▲                 • time comparison   27 strains   age 9-28wks   Inbred Crowley1 vertical activity [n]     baseline and  haloperidol       day:             • 0  ...... 867               • 30  ...... 469               • 60  ...... 434               • 120  ...... 733 ▲                 • time comparison   27 strains   age 9-28wks   Inbred   blood — xenobiotics — drug and metabolite concentration         mass spectrometry   Crowley1 plasma haloperidol concentration [nM]   haloperidol       day:             • 30  ...... 18.2               • 60  ...... 16.1               • 90  ...... 8.28               • 120  ...... 4.98                 • time comparison   27 strains   age 9-28wks   Inbred   body weight         scales   Crowley1 body weight [g]     baseline and  haloperidol       • starting  ...... 26.7         • ending  ...... 31.4           • time comparison   27 strains   age 9-28wks   Inbred

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