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MPD - Phenotype data: haloperidol
interventions
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haloperidol
(antipsychotic)
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behavior — balance and coordination
inclined screen test
Crowley1
extrapyramidal side effects (EPS) [s]
baseline and
haloperidol
day:
• 0
• 3
• 7
• 30
• 60
• 120
• time comparison
27
strains
age
9-28wks
Inbred
behavior — exploratory
open field test
Crowley1
center occupancy [%]
baseline and
haloperidol
day:
• 0
• 30
• 60
• 120
• time comparison
27
strains
age
9-28wks
Inbred
behavior — involuntary movement
observation
Crowley1
tongue protrusion [n]
baseline and
haloperidol
day:
• 0
• 30
• 60
• 120
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
overt chewing movement [n]
baseline and
haloperidol
day:
• 0
• 30
• 60
• 120
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
subtle chewing movement [n]
baseline and
haloperidol
day:
• 0
• 30
• 60
• 120
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
jaw tremor [s]
baseline and
haloperidol
day:
• 0
• 30
• 60
• 120
• time comparison
27
strains
age
9-28wks
Inbred
behavior — involuntary movement
open field test
Crowley1
repetitive behavior (stereotypy) [n]
baseline and
haloperidol
day:
• 0
• 30
• 60
• 120
• time comparison
27
strains
age
9-28wks
Inbred
behavior — locomotor activity
open field test
Crowley1
distance traveled [cm]
baseline and
haloperidol
day:
• 0
• 30
• 60
• 120
• time comparison
27
strains
age
9-28wks
Inbred
Crowley1
vertical activity [n]
baseline and
haloperidol
day:
• 0
• 30
• 60
• 120
• time comparison
27
strains
age
9-28wks
Inbred
blood — xenobiotics — drug and metabolite concentration
mass spectrometry
Crowley1
plasma haloperidol concentration [nM]
haloperidol
day:
• 30
• 60
• 90
• 120
• time comparison
27
strains
age
9-28wks
Inbred
body weight
scales
Crowley1
body weight [g]
baseline and
haloperidol
• starting
• ending
• time comparison
27
strains
age
9-28wks
Inbred
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