Home       About             Help       Phenotype data > PERA/EiJ strain > interventions > ethanol (alcohol EtOH)   See also:   Wikipedia Measurements: About these PERA/EiJ averages (♀ ♂) Exit PERA/EiJ mode behavior — balance and coordination         dowel balance test   Crabbe4 latency to fall [s]   ethanol 2g/kg i.p.       T0:             • 9.5mm  ......             • 15.8mm  ......               • comparison         T30:             • 9.5mm  ......             • 15.8mm  ......               • comparison   8 strains   age 12-16wks   Inbred   behavior — balance and coordination         rotarod   Crabbe3 fixed speed 3 rpm rotarod (latency to fall) [s]   ethanol       ethanol i.p. g/kg:             • 1  ......             • 2  ......             • 3  ......               • comparison   9 strains   age 9-17wks   Inbred Crabbe3 fixed speed 6 rpm rotarod (latency to fall) [s]   ethanol       ethanol i.p. g/kg:             • 1  ......             • 2  ......             • 3  ......               • comparison   9 strains   age 9-17wks   Inbred Crabbe3 fixed speed 10 rpm rotarod (latency to fall) [s]   ethanol       ethanol i.p. g/kg:             • 1  ......             • 2  ......             • 3  ......               • comparison   9 strains   age 9-17wks   Inbred Crabbe3 accelerating rotarod (latency to fall) - test day 1 20 rpm/min (ARR1) [s]     baseline and  ethanol       • baseline  ......       • ethanol  ......       • Δchange (ethanol effect)  ......       8 strains   age 9-17wks   Inbred Crabbe3 accelerating rotarod (latency to fall) - test day 2 30 rpm/min (ARR1) [s]     baseline and  ethanol       • baseline  ......       • ethanol  ......       • Δchange (ethanol effect)  ......       8 strains   age 9-17wks   Inbred Crabbe3 accelerating rotarod (latency to fall) - test 20 rpm/min (ARR2) [s]     baseline and  ethanol 2g/kg i.p.       • baseline  ...... 106 ▲▲   84.6 ▲         • ethanol  ...... 54.8   55.4         • Δchange (ethanol effect)  ...... -51.5 ▼▼   -29.2         • Δchange (saline control)  ...... 17.4   19.0 ▲         21 strains   age 9-17wks   Inbred   behavior — balance and coordination         vertical wire mesh   Crabbe4 latency to fall from a vertical wire mesh grid 30 min post-injection, screen test   [s] ......   ethanol 2g/kg i.p. 8 strains   age 9-10wks   Inbred   blood — xenobiotics — alcohol concentration         gas chromatography   Crabbe4 blood ethanol concentration (BEC), 35 min post-injection, dowel (15.8 mm) test   [mg/mL] ......   ethanol 2g/kg i.p. 8 strains   age 12-16wks   Inbred Crabbe4 blood ethanol levels following grip strength test at various times after treatment [mg/mL]   ethanol 2g/kg i.p.       time after ethanol:             • 30min  ...... 1.67   1.86 (N=4) ▲               • 60min  ...... 1.69   1.79 (N=4) ▲               • 105min  ...... 1.06   1.24 (N=4)               • 150min  ...... 0.386   0.562 (N=4)                 • time comparison   21 strains   age 7-12wks   Inbred   muscle — skeletal — function         grip strength   Crabbe4 grip strength test: peak force applied [g]     baseline and  ethanol 2g/kg i.p.       • baseline  ...... 115   129 (N=4)         • 30min after ethanol  ...... 95.8 ▲   82.6 (N=4)         • change (ethanol effect)  ...... 19.2 ▼   46.1 (N=4)         • % change (ethanol effect)  ...... 16.6 ▼   35.5 (N=4)         21 strains   age 7-12wks   Inbred

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