Home       About             Help       Phenotype data > SM/J strain > interventions > ethanol (alcohol EtOH)   See also:   Wikipedia Measurements: About these SM/J averages (♀ ♂) Exit SM/J mode behavior — balance and coordination         dowel balance test   Crabbe4 latency to fall [s]   ethanol   2g/kg i.p.       T0:             • 9.5mm  ......             • 15.8mm  ......               • comparison         T30:             • 9.5mm  ......             • 15.8mm  ......               • comparison   8 strains   age 12-16wks   Inbred   behavior — balance and coordination         rotarod   Crabbe3 fixed speed 3 rpm rotarod (latency to fall) [s]   ethanol       ethanol i.p. g/kg:             • 1  ......             • 2  ......             • 3  ......               • comparison   9 strains   age 9-17wks   Inbred Crabbe3 fixed speed 6 rpm rotarod (latency to fall) [s]   ethanol       ethanol i.p. g/kg:             • 1  ......             • 2  ......             • 3  ......               • comparison   9 strains   age 9-17wks   Inbred Crabbe3 fixed speed 10 rpm rotarod (latency to fall) [s]   ethanol       ethanol i.p. g/kg:             • 1  ......             • 2  ......             • 3  ......               • comparison   9 strains   age 9-17wks   Inbred Crabbe3 accelerating rotarod (latency to fall) - test day 1 20 rpm/min (ARR1) [s]     baseline and  ethanol various i.p.       • baseline  ......       • ethanol  ......       • Δchange (ethanol effect)  ......       8 strains   age 9-17wks   Inbred Crabbe3 accelerating rotarod (latency to fall) - test day 2 30 rpm/min (ARR1) [s]     baseline and  ethanol various i.p.       • baseline  ......       • ethanol  ......       • Δchange (ethanol effect)  ......       8 strains   age 9-17wks   Inbred Crabbe3 accelerating rotarod (latency to fall) - test 20 rpm/min (ARR2) [s]     baseline and  ethanol 2g/kg i.p.       • baseline  ...... 66.9   63.2         • ethanol  ...... 44.3   43.0         • Δchange (ethanol effect)  ...... -22.5   -20.3         • Δchange (saline control)  ...... 9.14   9.85         21 strains   age 9-17wks   Inbred   behavior — balance and coordination         vertical wire mesh   Crabbe4 latency to fall from a vertical wire mesh grid 30 min post-injection, screen test   [s] ......   ethanol   2g/kg i.p. 8 strains   age 9-10wks   Inbred   blood — xenobiotics — alcohol concentration         gas chromatography   Crabbe4 blood ethanol concentration (BEC), 35 min post-injection, dowel (15.8 mm) test   [mg/mL] ......   ethanol   2g/kg i.p. 8 strains   age 12-16wks   Inbred Crabbe4 blood ethanol levels following grip strength test at various times after treatment [mg/mL]   ethanol   2g/kg i.p.       time after ethanol:             • 30min  ...... 1.93 ▲   1.67               • 60min  ...... 1.74 ▲   1.64               • 105min  ...... 1.15   0.995 ▼               • 150min  ...... 0.558   0.515                 • time comparison   21 strains   age 7-12wks   Inbred   muscle — skeletal — function         grip strength   Crabbe4 grip strength test: peak force applied [g]     baseline and  ethanol 2g/kg i.p.       • baseline  ...... 94.8   138         • 30min after ethanol  ...... 40.3 ▼   54.5         • change (ethanol effect)  ...... 54.4 ▲   84.1 ▲         • % change (ethanol effect)  ...... 57.2 ▲   60.2 ▲         21 strains   age 7-12wks   Inbred

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