Home       About             Help       Phenotype data > interventions > ethanol (alcohol EtOH)   See also:   Wikipedia   QTL data   Investigators, papers, protocols           Ontologies Measurements: Apply tools basic list show overall averages show C57BL/6J averages show variable names verbose descriptions with checkboxes behavior — balance and coordination         balance beam   Crabbe1 missteps crossing balance beam [n]     control and  ethanol       12.7mm beam: • control    i.p. doses g/kg: • 1.0  • 1.2  • 1.4    • comparison   8 strains   age 8-16wks   Inbred Crabbe1 missteps crossing balance beam [n]     control and  ethanol       15.8mm beam: • control    i.p. doses g/kg: • 1.0  • 1.2  • 1.4    • comparison   8 strains   age 8-16wks   Inbred Crabbe1 missteps crossing balance beam [n]     control and  ethanol       19.0mm beam: • control    i.p. doses g/kg: • 1.0  • 1.2  • 1.4    • comparison   8 strains   age 8-16wks   Inbred   behavior — balance and coordination         dowel balance test   Crabbe4 latency to fall [s]   ethanol   2g/kg i.p.         T0:   • 9.5mm    • 15.8mm    • comparison           T30:   • 9.5mm    • 15.8mm    • comparison   8 strains   age 12-16wks   Inbred   behavior — balance and coordination         grid test   Crabbe1 grid habituation, distance traveled [cm]     control and  ethanol       • control    i.p. doses g/kg: • 1.5  • 2.0  • 2.5    • comparison   8 strains   age 8-16wks   Inbred Crabbe1 grid habituation, missteps per cm [n/cm]     control and  ethanol       • control    i.p. doses g/kg: • 1.5  • 2.0  • 2.5    • comparison   8 strains   age 8-16wks   Inbred   behavior — balance and coordination         parallel rod floor test   Crabbe5 motor incoordination (errors/distance traveled) 1.6mm rod, 6mm space [n/cm]     control and  ethanol       • day1 control   • day2 control   • day3 ethanol    • comparison   8 strains   age 7-14wks   Inbred   behavior — balance and coordination         rotarod   Crabbe3 fixed speed 3 rpm rotarod (latency to fall) [s]   ethanol       ethanol i.p. g/kg: • 1  • 2  • 3    • comparison   9 strains   age 9-17wks   Inbred Crabbe3 fixed speed 6 rpm rotarod (latency to fall) [s]   ethanol       ethanol i.p. g/kg: • 1  • 2  • 3    • comparison   9 strains   age 9-17wks   Inbred Crabbe3 fixed speed 10 rpm rotarod (latency to fall) [s]   ethanol       ethanol i.p. g/kg: • 1  • 2  • 3    • comparison   9 strains   age 9-17wks   Inbred Crabbe3 accelerating rotarod (latency to fall) - test day 1 20 rpm/min (ARR1) [s]     baseline and  ethanol various i.p.       • baseline  • ethanol  • Δchange (ethanol effect)  8 strains   age 9-17wks   Inbred Crabbe3 accelerating rotarod (latency to fall) - test day 2 30 rpm/min (ARR1) [s]     baseline and  ethanol various i.p.       • baseline  • ethanol  • Δchange (ethanol effect)  8 strains   age 9-17wks   Inbred Crabbe3 accelerating rotarod (latency to fall) - test 20 rpm/min (ARR2) [s]     baseline and  ethanol 2g/kg i.p.       • baseline   • ethanol   • Δchange (ethanol effect)   • Δchange (saline control)  21 strains   age 9-17wks   Inbred   behavior — balance and coordination         vertical wire mesh   Crabbe4 latency to fall from a vertical wire mesh grid 30 min post-injection, screen test   [s]   ethanol   2g/kg i.p. 8 strains   age 9-10wks   Inbred   behavior — balance and coordination — observer-rated ataxia         observation   Metten1 hindlimb splay, 2.75 g/kg injection [score]   ethanol   2.75g/kg i.p.       • 10min after injection  • 30min after    • comparison   9 strains   age 8-11wks   Inbred Metten1 hindlimb splay, 3.0 g/kg injection [score]   ethanol   3.0g/kg i.p.       • 10min after injection  • 30min after    • comparison   9 strains   age 8-11wks   Inbred Metten1 erratic gait, 2.75 g/kg injection [score]   ethanol   2.75g/kg i.p.       • 10min after injection  • 30min after    • comparison   9 strains   age 8-11wks   Inbred Metten1 erratic gait, 3.0 g/kg injection [score]   ethanol   3.0g/kg i.p.       • 10min after injection  • 30min after    • comparison   9 strains   age 8-11wks   Inbred Metten1 compare dose groups, hindlimb splay   ethanol         10min after  30min after  9 strains   age 8-11wks   Inbred Metten1 compare dose groups, eratic gait   ethanol         10min after  30min after  9 strains   age 8-11wks   Inbred   behavior — involuntary movement — handling-induced convulsion         observation   Metten2 peak handling-induced convulsion score [score]     control and  ethanol aerosolized       • control   • ethanol   • ethanol normalized to controls  15 strains   age 8-15wks   Inbred Metten2 latency to first score used to calculate peak ethanol   [h]   ethanol   aerosolized 15 strains   age 8-15wks   Inbred Metten2 withdrawal severity during 0-25h (area under curve of HIC scores) [AUC]   ethanol   aerosolized       • ethanol   • ethanol normalized to controls  15 strains   age 8-15wks   Inbred   behavior — locomotor activity         open field test   Metten1 line crossings, 2.75 g/kg injection [n]     control and  ethanol 2.75g/kg i.p.       • pre-injection  • 10min after injection  • 30min after    • comparison   9 strains   age 8-11wks   Inbred Metten1 line crossings, 3.0 g/kg injection [n]     control and  ethanol 3.0g/kg i.p.       • pre-injection  • 10min after injection  • 30min after    • comparison   9 strains   age 8-11wks   Inbred Metten1 line crossings, compare dose groups     control and  ethanol       pre-injection  10min after injection  30min after  9 strains   age 8-11wks   Inbred   behavior — locomotor activity         parallel rod floor test   Crabbe5 distance traveled, 1.6mm rod, 6mm space [cm]     control and  ethanol       • day1 control   • day2 control   • day3 ethanol    • comparison   8 strains   age 8-10wks   Inbred   blood — xenobiotics — alcohol concentration         gas chromatography   Crabbe4 blood ethanol concentration (BEC), 35 min post-injection, dowel (15.8 mm) test   [mg/mL]   ethanol   2g/kg i.p. 8 strains   age 12-16wks   Inbred Crabbe4 blood ethanol levels following grip strength test at various times after treatment [mg/mL]   ethanol   2g/kg i.p.       time after ethanol:    • 30min  • 60min  • 105min  • 150min    • time comparison   21 strains   age 7-12wks   Inbred   blood — xenobiotics — alcohol concentration         spectrophotometry   Bennett3 blood ethanol concentration (BEC) [mg/mL]   ethanol         • first loss of balance (ataxia)  • first regain of balance  • second regain of balance    • comparison   72 strains   age 8-14wks   ILSXISS Bennett3 acute functional tolerance to two-stage injections of EtOH [mg/mL]   ethanol         • as a function of first regain of balance  • as a function of first loss of balance    • comparison   72 strains   age 8-14wks   ILSXISS   muscle — skeletal — function         grip strength   Crabbe4 grip strength test: peak force applied [g]     baseline and  ethanol 2g/kg i.p.       • baseline  • 30min after ethanol        • change (ethanol effect)  • % change (ethanol effect)  21 strains   age 7-12wks   Inbred

If you're focusing on one or two particular mouse strains click here to begin.
Video tutorial session 2 explains the use of this page.

Hosted by:

Contact us About MPD Also at JAX

Units Changelog Downloads

Citing Funding Terms of Use