|
body weight
scales
|
|
|
fold change in body weight over testing period
[ratio]
control and
atenolol, isoproterenol
......
1.02
......
1.02
......
1.06
......
0.996
|
Inbred
|
| |
|
cardiovascular — blood pressure
tail cuff
|
|
|
systolic blood pressure
[mmHg]
control and
atenolol, isoproterenol
......
104
......
101
......
94.4
......
105
|
Inbred
|
| |
|
cardiovascular — ECG parameters — unconscious
ECG
|
|
|
amplitude of P-wave
[mV]
control and
atenolol, isoproterenol
......
0.167
......
0.139
......
0.178
......
0.186
|
Inbred
|
|
|
amplitude of Q-wave
[mV]
control and
atenolol, isoproterenol
......
-0.0192
......
-0.0322
......
-0.0226
......
-0.0199
|
Inbred
|
|
|
amplitude of R-wave
[mV]
control and
atenolol, isoproterenol
......
0.353
......
0.489
......
0.440
......
0.822
|
Inbred
|
|
|
amplitude of S-wave
[mV]
control and
atenolol, isoproterenol
......
-0.274
(N=4)
......
-0.133
(N=3)
......
-0.177
(N=4)
......
-0.108
|
Inbred
|
|
|
duration P-wave
[ms]
control and
atenolol, isoproterenol
......
12.4
......
14.0
......
13.6
......
13.1
|
Inbred
|
|
|
interval PR
[ms]
control and
atenolol, isoproterenol
......
38.2
......
39.4
......
36.9
......
33.2
|
Inbred
|
|
|
interval RR
[ms]
control and
atenolol, isoproterenol
......
163
......
200
......
137
......
151
|
Inbred
|
|
|
interval QRS
[ms]
control and
atenolol, isoproterenol
......
11.9
......
13.7
......
10.9
......
10.7
|
Inbred
|
|
|
interval QT
[ms]
control and
atenolol, isoproterenol
......
62.1
......
69.1
......
62.2
......
56.8
|
Inbred
|
|
|
interval ST
[ms]
control and
atenolol, isoproterenol
......
50.2
......
55.4
......
51.3
......
40.1
|
Inbred
|
|
|
area of P-wave
[ms*mV]
control and
atenolol, isoproterenol
......
1.06
......
1.05
......
1.20
......
1.20
|
Inbred
|
|
|
area of QRS
[ms*mV]
control and
atenolol, isoproterenol
......
0.706
......
1.70
(N=3)
......
1.29
......
2.53
|
Inbred
|
|
|
area of QTc
[ms*mV]
control and
atenolol, isoproterenol
......
48.8
......
49.2
......
53.4
......
45.8
|
Inbred
|
| |
|
cardiovascular — heart rate — conscious
tail cuff
|
|
|
pulse rate
[n/min]
control and
atenolol, isoproterenol
......
589
......
480
......
758
......
734
|
Inbred
|
| |
|
cardiovascular — heart rate — unconscious
ECG
|
|
|
heart rate
[n/min]
control and
atenolol, isoproterenol
......
370
......
312
......
440
......
402
|
Inbred
|
| |
|
cardiovascular — heart weight
scales
|
|
|
heart weight
[mg]
control and
atenolol, isoproterenol
weight:
......
118
......
110
......
111
......
131
normalized:
......
5.01
......
4.87
......
4.88
......
5.80
|
Inbred
|
|
|
atria weight
[mg]
control and
atenolol, isoproterenol
weight:
......
6.68
......
6.25
......
6.76
......
8.21
normalized:
......
0.284
......
0.276
......
0.296
......
0.362
|
Inbred
|
|
|
ventricle (both) weight
[mg]
control and
atenolol, isoproterenol
weight:
......
111
......
104
......
105
......
123
normalized:
......
4.73
......
4.59
......
4.58
......
5.44
|
Inbred
|
|
|
atria weight to ventricle weight ratio
[ratio]
control and
atenolol, isoproterenol
......
16.8
......
16.8
......
15.5
......
15.1
|
Inbred
|