Home       About             Help       Phenotype data > C3H/HeJ strain > interventions > atenolol, isoproterenol   Measurements: About these C3H/HeJ averages (♀ ♂) Exit C3H/HeJ mode body weight         scales   Maurer1 fold change in body weight over testing period [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 1.03         • atenolol 10mg  ...... 1.07         • isoprot 1mg  ...... 1.07         • isoprot 10mg  ...... 1.10           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — blood pressure         tail cuff   Maurer1 systolic blood pressure [mmHg]     control and  atenolol, isoproterenol2wks       • control  ...... 99.8         • atenolol 10mg  ...... 94.5         • isoprot 1mg  ...... 82.6 ▼         • isoprot 10mg  ...... 101           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — ECG parameters — unconscious         ECG   Maurer1 amplitude of P-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.111         • atenolol 10mg  ...... 0.113         • isoprot 1mg  ...... 0.129         • isoprot 10mg  ...... 0.119           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of Q-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.0530         • atenolol 10mg  ...... -0.0329         • isoprot 1mg  ...... -0.0589 ▼         • isoprot 10mg  ...... -0.0667 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of R-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.368 ▼         • atenolol 10mg  ...... 0.301 ▼         • isoprot 1mg  ...... 0.247 ▼         • isoprot 10mg  ...... 0.290 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of S-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.379 ▼         • atenolol 10mg  ...... -0.258         • isoprot 1mg  ...... -0.376 ▼         • isoprot 10mg  ...... -0.370 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 duration P-wave [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 11.1         • atenolol 10mg  ...... 12.4         • isoprot 1mg  ...... 10.7         • isoprot 10mg  ...... 10.0           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval PR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 37.6         • atenolol 10mg  ...... 40.2         • isoprot 1mg  ...... 38.2         • isoprot 10mg  ...... 36.7           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval RR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 134         • atenolol 10mg  ...... 172         • isoprot 1mg  ...... 113         • isoprot 10mg  ...... 112           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QRS [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 12.1         • atenolol 10mg  ...... 11.6 ▼         • isoprot 1mg  ...... 9.98 ▼         • isoprot 10mg  ...... 9.57 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QT [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 51.7         • atenolol 10mg  ...... 52.0 ▼         • isoprot 1mg  ...... 45.3 ▼         • isoprot 10mg  ...... 41.9 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval ST [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 39.5         • atenolol 10mg  ...... 40.5         • isoprot 1mg  ...... 35.2         • isoprot 10mg  ...... 32.3 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of P-wave [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.575         • atenolol 10mg  ...... 0.700         • isoprot 1mg  ...... 0.622         • isoprot 10mg  ...... 0.559           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QRS [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.0570 ▼         • atenolol 10mg  ...... 0.286 ▼         • isoprot 1mg  ...... -0.324 ▼▼         • isoprot 10mg  ...... -0.248 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QTc [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 44.9         • atenolol 10mg  ...... 40.0 ▼         • isoprot 1mg  ...... 42.4 ▼         • isoprot 10mg  ...... 39.7 ▼           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — conscious         tail cuff   Maurer1 pulse rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 607         • atenolol 10mg  ...... 524         • isoprot 1mg  ...... 826         • isoprot 10mg  ...... 783           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — unconscious         ECG   Maurer1 heart rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 457         • atenolol 10mg  ...... 357         • isoprot 1mg  ...... 530         • isoprot 10mg  ...... 538           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart weight         scales   Maurer1 heart weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 91.7               • atenolol 10mg  ...... 92.8               • isoprot 1mg  ...... 95.3               • isoprot 10mg  ...... 111                 • comparison         normalized:             • control  ...... 3.68 ▼               • atenolol 10mg  ...... 3.58 ▼               • isoprot 1mg  ...... 3.76 ▼               • isoprot 10mg  ...... 4.18 ▼                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 5.35               • atenolol 10mg  ...... 5.92               • isoprot 1mg  ...... 6.39               • isoprot 10mg  ...... 7.59                 • comparison         normalized:             • control  ...... 0.215               • atenolol 10mg  ...... 0.227               • isoprot 1mg  ...... 0.253               • isoprot 10mg  ...... 0.288                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 ventricle (both) weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 86.3               • atenolol 10mg  ...... 86.8               • isoprot 1mg  ...... 88.9               • isoprot 10mg  ...... 103                 • comparison         normalized:             • control  ...... 3.46 ▼               • atenolol 10mg  ...... 3.35 ▼               • isoprot 1mg  ...... 3.51 ▼               • isoprot 10mg  ...... 3.90 ▼                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 16.5         • atenolol 10mg  ...... 14.8         • isoprot 1mg  ...... 14.1         • isoprot 10mg  ...... 13.7           • comparison   23 strains   age 7-13wks   Inbred

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