Home       About             Help       Phenotype data > SM/J strain > interventions > atenolol, isoproterenol   Measurements: About these SM/J averages (♀ ♂) Exit SM/J mode body weight         scales   Maurer1 fold change in body weight over testing period [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 1.09 ▲         • atenolol 10mg  ...... 1.08         • isoprot 1mg  ...... 1.09         • isoprot 10mg  ...... 1.14 ▲           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — blood pressure         tail cuff   Maurer1 systolic blood pressure [mmHg]     control and  atenolol, isoproterenol2wks       • control  ...... 107         • atenolol 10mg  ...... 107         • isoprot 1mg  ...... 97.6         • isoprot 10mg  ...... 106           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — ECG parameters — unconscious         ECG   Maurer1 amplitude of P-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.136 ▲         • atenolol 10mg  ...... 0.128 ▲         • isoprot 1mg  ...... 0.137         • isoprot 10mg  ...... 0.136           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of Q-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.0129         • atenolol 10mg  ...... -0.0250         • isoprot 1mg  ...... -0.0177         • isoprot 10mg  ...... -0.0917 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of R-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.681         • atenolol 10mg  ...... 0.491         • isoprot 1mg  ...... 0.471         • isoprot 10mg  ...... 0.513           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of S-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.643 ▼▼         • atenolol 10mg  ...... -0.518 ▼▼         • isoprot 1mg  ...... -0.548 ▼▼         • isoprot 10mg  ...... -0.595 ▼▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 duration P-wave [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 11.4         • atenolol 10mg  ...... 11.2 ▼         • isoprot 1mg  ...... 10.1         • isoprot 10mg  ...... 10.4           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval PR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 38.5         • atenolol 10mg  ...... 39.6         • isoprot 1mg  ...... 38.8         • isoprot 10mg  ...... 33.9           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval RR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 123         • atenolol 10mg  ...... 142         • isoprot 1mg  ...... 112         • isoprot 10mg  ...... 101 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QRS [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 13.4         • atenolol 10mg  ...... 14.6 ▲         • isoprot 1mg  ...... 11.2         • isoprot 10mg  ...... 10.6           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QT [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 61.8 ▲         • atenolol 10mg  ...... 61.5         • isoprot 1mg  ...... 58.4 ▲         • isoprot 10mg  ...... 54.8           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval ST [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 48.8 ▲         • atenolol 10mg  ...... 47.4         • isoprot 1mg  ...... 47.1 ▲         • isoprot 10mg  ...... 44.9 ▲           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of P-wave [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.719         • atenolol 10mg  ...... 0.703         • isoprot 1mg  ...... 0.660         • isoprot 10mg  ...... 0.660           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QRS [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.0536 ▼         • atenolol 10mg  ...... -0.422 ▼▼         • isoprot 1mg  ...... 0.162 ▼         • isoprot 10mg  ...... 0.296 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QTc [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 55.5 ▲         • atenolol 10mg  ...... 51.6 ▲         • isoprot 1mg  ...... 55.1 ▲         • isoprot 10mg  ...... 55.1 ▲           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — conscious         tail cuff   Maurer1 pulse rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 614         • atenolol 10mg  ...... 534         • isoprot 1mg  ...... 771         • isoprot 10mg  ...... 810           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — unconscious         ECG   Maurer1 heart rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 488         • atenolol 10mg  ...... 423         • isoprot 1mg  ...... 538         • isoprot 10mg  ...... 594 ▲           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart weight         scales   Maurer1 heart weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 85.8 ▼               • atenolol 10mg  ...... 83.3 ▼               • isoprot 1mg  ...... 92.9 ▼               • isoprot 10mg  ...... 113                 • comparison         normalized:             • control  ...... 4.77               • atenolol 10mg  ...... 4.51               • isoprot 1mg  ...... 5.01 ▲               • isoprot 10mg  ...... 5.76 ▲                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 4.48 ▼               • atenolol 10mg  ...... 4.41 ▼               • isoprot 1mg  ...... 5.62 ▼               • isoprot 10mg  ...... 7.18                 • comparison         normalized:             • control  ...... 0.247               • atenolol 10mg  ...... 0.241               • isoprot 1mg  ...... 0.303               • isoprot 10mg  ...... 0.364 ▲                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 ventricle (both) weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 81.3 ▼               • atenolol 10mg  ...... 79.2 ▼               • isoprot 1mg  ...... 87.3 ▼               • isoprot 10mg  ...... 106                 • comparison         normalized:             • control  ...... 4.52               • atenolol 10mg  ...... 4.29               • isoprot 1mg  ...... 4.71 ▲               • isoprot 10mg  ...... 5.39 ▲                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 18.7         • atenolol 10mg  ...... 18.2         • isoprot 1mg  ...... 15.9         • isoprot 10mg  ...... 15.0           • comparison   23 strains   age 7-13wks   Inbred

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