Home       About             Help       Phenotype data > I/LnJ strain > interventions > atenolol, isoproterenol   Measurements: About these I/LnJ averages (♀ ♂) Exit I/LnJ mode body weight         scales   Maurer1 fold change in body weight over testing period [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 1.03         • atenolol 10mg  ...... 1.07         • isoprot 1mg  ...... 1.06         • isoprot 10mg  ...... 1.09           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — blood pressure         tail cuff   Maurer1 systolic blood pressure [mmHg]     control and  atenolol, isoproterenol2wks       • control  ...... 99.7         • atenolol 10mg  ...... 84.6 ▼         • isoprot 1mg  ...... 92.5         • isoprot 10mg  ...... 94.9 ▼           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — ECG parameters — unconscious         ECG   Maurer1 amplitude of P-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.148 ▲         • atenolol 10mg  ...... 0.137 ▲         • isoprot 1mg  ...... 0.153 ▲         • isoprot 10mg  ...... 0.159 ▲           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of Q-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.0280         • atenolol 10mg  ...... -0.0344         • isoprot 1mg  ...... -0.00222         • isoprot 10mg  ...... -0.0200           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of R-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.590         • atenolol 10mg  ...... 0.637         • isoprot 1mg  ...... 0.644         • isoprot 10mg  ...... 0.766           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of S-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.111 ▲         • atenolol 10mg  ...... -0.0578 ▲         • isoprot 1mg  ...... -0.111 ▲         • isoprot 10mg  ...... -0.122           • comparison   23 strains   age 7-13wks   Inbred Maurer1 duration P-wave [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 10.8 ▼         • atenolol 10mg  ...... 11.5         • isoprot 1mg  ...... 9.85 ▼         • isoprot 10mg  ...... 10.4           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval PR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 33.3 ▼         • atenolol 10mg  ...... 33.7 ▼         • isoprot 1mg  ...... 30.9 ▼         • isoprot 10mg  ...... 29.6 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval RR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 152         • atenolol 10mg  ...... 183 ▲         • isoprot 1mg  ...... 114         • isoprot 10mg  ...... 117           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QRS [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 9.40 ▼▼         • atenolol 10mg  ...... 11.4 ▼         • isoprot 1mg  ...... 10.7 ▼         • isoprot 10mg  ...... 11.4           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QT [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 62.9 ▲         • atenolol 10mg  ...... 65.9 ▲         • isoprot 1mg  ...... 42.6 ▼         • isoprot 10mg  ...... 52.6           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval ST [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 54.5 ▲▲         • atenolol 10mg  ...... 65.3 ▲▲         • isoprot 1mg  ...... 31.5 ▼         • isoprot 10mg  ...... 44.4           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of P-wave [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.724         • atenolol 10mg  ...... 0.746         • isoprot 1mg  ...... 0.750         • isoprot 10mg  ...... 0.757           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QRS [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 1.67         • atenolol 10mg  ...... 2.12         • isoprot 1mg  ...... 2.08         • isoprot 10mg  ...... 2.10           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QTc [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 50.8         • atenolol 10mg  ...... 49.6         • isoprot 1mg  ...... 40.1 ▼         • isoprot 10mg  ...... 48.8           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — conscious         tail cuff   Maurer1 pulse rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 621         • atenolol 10mg  ...... 531         • isoprot 1mg  ...... 818         • isoprot 10mg  ...... 877 ▲           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — unconscious         ECG   Maurer1 heart rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 410         • atenolol 10mg  ...... 332 ▼         • isoprot 1mg  ...... 533         • isoprot 10mg  ...... 519           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart weight         scales   Maurer1 heart weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 104               • atenolol 10mg  ...... 106               • isoprot 1mg  ...... 116               • isoprot 10mg  ...... 129                 • comparison         normalized:             • control  ...... 4.72               • atenolol 10mg  ...... 4.74 ▲               • isoprot 1mg  ...... 4.77               • isoprot 10mg  ...... 5.45                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 6.92 ▲               • atenolol 10mg  ...... 6.89 ▲               • isoprot 1mg  ...... 8.19 ▲               • isoprot 10mg  ...... 9.75 ▲                 • comparison         normalized:             • control  ...... 0.314 ▲▲               • atenolol 10mg  ...... 0.309 ▲▲               • isoprot 1mg  ...... 0.336 ▲               • isoprot 10mg  ...... 0.412 ▲▲                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 ventricle (both) weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 97.3               • atenolol 10mg  ...... 99.2               • isoprot 1mg  ...... 108               • isoprot 10mg  ...... 119                 • comparison         normalized:             • control  ...... 4.40               • atenolol 10mg  ...... 4.43 ▲               • isoprot 1mg  ...... 4.44               • isoprot 10mg  ...... 5.04                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 14.3 ▼         • atenolol 10mg  ...... 14.4 ▼         • isoprot 1mg  ...... 13.3         • isoprot 10mg  ...... 12.3 ▼           • comparison   23 strains   age 7-13wks   Inbred

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