Home       About             Help       Phenotype data > 129S1/SvImJ strain > interventions > atenolol, isoproterenol   Measurements: About these 129S1/SvImJ averages (♀ ♂) Exit 129S1/SvImJ mode body weight         scales   Maurer1 fold change in body weight over testing period [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 0.976 ▼         • atenolol 10mg  ...... 1.00         • isoprot 1mg  ...... 1.06         • isoprot 10mg  ...... 1.12           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — blood pressure         tail cuff   Maurer1 systolic blood pressure [mmHg]     control and  atenolol, isoproterenol2wks       • control  ...... 112         • atenolol 10mg  ...... 111 ▲         • isoprot 1mg  ...... 102         • isoprot 10mg  ...... 109           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — ECG parameters — unconscious         ECG   Maurer1 amplitude of P-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.137 ▲         • atenolol 10mg  ...... 0.122         • isoprot 1mg  ...... 0.164 ▲         • isoprot 10mg  ...... 0.156 ▲           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of Q-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.0531         • atenolol 10mg  ...... -0.0577         • isoprot 1mg  ...... -0.0115         • isoprot 10mg  ...... -0.0208           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of R-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.655         • atenolol 10mg  ...... 0.677         • isoprot 1mg  ...... 0.706         • isoprot 10mg  ...... 0.578           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of S-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.310         • atenolol 10mg  ...... -0.345 ▼         • isoprot 1mg  ...... -0.482 ▼▼         • isoprot 10mg  ...... -0.402 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 duration P-wave [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 12.3         • atenolol 10mg  ...... 13.2         • isoprot 1mg  ...... 11.9         • isoprot 10mg  ...... 11.8           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval PR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 45.7 ▲         • atenolol 10mg  ...... 47.2 ▲         • isoprot 1mg  ...... 41.9 ▲         • isoprot 10mg  ...... 38.9           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval RR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 132         • atenolol 10mg  ...... 149         • isoprot 1mg  ...... 109         • isoprot 10mg  ...... 106           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QRS [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 14.6 ▲         • atenolol 10mg  ...... 14.8 ▲         • isoprot 1mg  ...... 13.4 ▲         • isoprot 10mg  ...... 12.6           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QT [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 58.3         • atenolol 10mg  ...... 57.2         • isoprot 1mg  ...... 49.6         • isoprot 10mg  ...... 52.2           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval ST [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 43.8         • atenolol 10mg  ...... 42.5         • isoprot 1mg  ...... 36.2         • isoprot 10mg  ...... 39.6           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of P-wave [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.720         • atenolol 10mg  ...... 0.672         • isoprot 1mg  ...... 0.863 ▲         • isoprot 10mg  ...... 0.838 ▲           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QRS [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 1.13         • atenolol 10mg  ...... 0.970         • isoprot 1mg  ...... 0.608         • isoprot 10mg  ...... 0.573           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QTc [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 50.7         • atenolol 10mg  ...... 46.9         • isoprot 1mg  ...... 47.4         • isoprot 10mg  ...... 50.8           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — conscious         tail cuff   Maurer1 pulse rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 583         • atenolol 10mg  ...... 512         • isoprot 1mg  ...... 757         • isoprot 10mg  ...... 824           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — unconscious         ECG   Maurer1 heart rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 458         • atenolol 10mg  ...... 406         • isoprot 1mg  ...... 551         • isoprot 10mg  ...... 570           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart weight         scales   Maurer1 heart weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 96.4               • atenolol 10mg  ...... 99.0               • isoprot 1mg  ...... 116               • isoprot 10mg  ...... 153 ▲                 • comparison         normalized:             • control  ...... 4.68               • atenolol 10mg  ...... 4.66               • isoprot 1mg  ...... 4.95 ▲               • isoprot 10mg  ...... 6.25 ▲▲                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 3.95 ▼               • atenolol 10mg  ...... 4.61 ▼               • isoprot 1mg  ...... 5.31 ▼               • isoprot 10mg  ...... 7.05                 • comparison         normalized:             • control  ...... 0.191 ▼               • atenolol 10mg  ...... 0.216 ▼               • isoprot 1mg  ...... 0.229 ▼               • isoprot 10mg  ...... 0.289                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 ventricle (both) weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 92.5               • atenolol 10mg  ...... 94.4               • isoprot 1mg  ...... 110               • isoprot 10mg  ...... 146 ▲                 • comparison         normalized:             • control  ...... 4.49               • atenolol 10mg  ...... 4.44 ▲               • isoprot 1mg  ...... 4.72 ▲               • isoprot 10mg  ...... 5.97 ▲▲                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 24.9 ▲▲         • atenolol 10mg  ...... 20.8 ▲▲         • isoprot 1mg  ...... 21.8 ▲▲         • isoprot 10mg  ...... 20.9 ▲▲           • comparison   23 strains   age 7-13wks   Inbred

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