Home       About             Help       Phenotype data > SJL/J strain > interventions > atenolol, isoproterenol   Measurements: About these SJL/J averages (♀ ♂) Exit SJL/J mode body weight         scales   Maurer1 fold change in body weight over testing period [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 0.990 ▼         • atenolol 10mg  ...... 0.987         • isoprot 1mg  ...... 1.07         • isoprot 10mg  ...... 1.08           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — blood pressure         tail cuff   Maurer1 systolic blood pressure [mmHg]     control and  atenolol, isoproterenol2wks       • control  ...... 88.9 ▼         • atenolol 10mg  ...... 82.8 ▼         • isoprot 1mg  ...... 72.6 ▼▼         • isoprot 10mg  ...... 91.7 ▼           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — ECG parameters — unconscious         ECG   Maurer1 amplitude of P-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.0989         • atenolol 10mg  ...... 0.0956         • isoprot 1mg  ...... 0.0822         • isoprot 10mg  ...... 0.106           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of Q-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.00222 ▲         • atenolol 10mg  ...... -0.0138         • isoprot 1mg  ...... -0.00778         • isoprot 10mg  ...... -0.00500           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of R-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.442         • atenolol 10mg  ...... 0.467         • isoprot 1mg  ...... 0.402         • isoprot 10mg  ...... 0.617           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of S-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.121         • atenolol 10mg  ...... -0.118         • isoprot 1mg  ...... -0.121 ▲         • isoprot 10mg  ...... -0.116           • comparison   23 strains   age 7-13wks   Inbred Maurer1 duration P-wave [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 11.6         • atenolol 10mg  ...... 12.4         • isoprot 1mg  ...... 10.6         • isoprot 10mg  ...... 11.2           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval PR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 42.5         • atenolol 10mg  ...... 44.6         • isoprot 1mg  ...... 41.2         • isoprot 10mg  ...... 36.9           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval RR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 118         • atenolol 10mg  ...... 140         • isoprot 1mg  ...... 120         • isoprot 10mg  ...... 115           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QRS [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 10.9 ▼         • atenolol 10mg  ...... 12.7         • isoprot 1mg  ...... 13.0         • isoprot 10mg  ...... 11.7           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QT [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 43.1 ▼▼         • atenolol 10mg  ...... 48.9 ▼         • isoprot 1mg  ...... 44.8 ▼         • isoprot 10mg  ...... 39.0 ▼▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval ST [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 31.9 ▼         • atenolol 10mg  ...... 36.8 ▼         • isoprot 1mg  ...... 31.6 ▼         • isoprot 10mg  ...... 26.6 ▼▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of P-wave [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.552         • atenolol 10mg  ...... 0.602         • isoprot 1mg  ...... 0.433         • isoprot 10mg  ...... 0.545           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QRS [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 1.61         • atenolol 10mg  ...... 1.62         • isoprot 1mg  ...... 1.43         • isoprot 10mg  ...... 2.19           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QTc [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 39.8 ▼         • atenolol 10mg  ...... 42.6         • isoprot 1mg  ...... 40.9 ▼         • isoprot 10mg  ...... 36.4 ▼▼           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — conscious         tail cuff   Maurer1 pulse rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 713 ▲         • atenolol 10mg  ...... 588 ▲         • isoprot 1mg  ...... 875 ▲▲         • isoprot 10mg  ...... 842 ▲           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — unconscious         ECG   Maurer1 heart rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 515 ▲         • atenolol 10mg  ...... 438         • isoprot 1mg  ...... 504         • isoprot 10mg  ...... 522           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart weight         scales   Maurer1 heart weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 92.5               • atenolol 10mg  ...... 91.7               • isoprot 1mg  ...... 100               • isoprot 10mg  ...... 112                 • comparison         normalized:             • control  ...... 4.16               • atenolol 10mg  ...... 4.18               • isoprot 1mg  ...... 4.16               • isoprot 10mg  ...... 4.52                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 5.71               • atenolol 10mg  ...... 5.88               • isoprot 1mg  ...... 7.30               • isoprot 10mg  ...... 7.79                 • comparison         normalized:             • control  ...... 0.257               • atenolol 10mg  ...... 0.268               • isoprot 1mg  ...... 0.302               • isoprot 10mg  ...... 0.315                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 ventricle (both) weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 86.9               • atenolol 10mg  ...... 85.8               • isoprot 1mg  ...... 93.0               • isoprot 10mg  ...... 104                 • comparison         normalized:             • control  ...... 3.91               • atenolol 10mg  ...... 3.91               • isoprot 1mg  ...... 3.85               • isoprot 10mg  ...... 4.21                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 15.4         • atenolol 10mg  ...... 14.8         • isoprot 1mg  ...... 12.9 ▼         • isoprot 10mg  ...... 13.4           • comparison   23 strains   age 7-13wks   Inbred

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