Home       About             Help       Phenotype data > SWR/J strain > interventions > atenolol, isoproterenol   Measurements: About these SWR/J averages (♀ ♂) Exit SWR/J mode body weight         scales   Maurer1 fold change in body weight over testing period [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 1.01         • atenolol 10mg  ...... 1.03         • isoprot 1mg  ...... 1.04         • isoprot 10mg  ...... 1.13           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — blood pressure         tail cuff   Maurer1 systolic blood pressure [mmHg]     control and  atenolol, isoproterenol2wks       • control  ...... 119 ▲         • atenolol 10mg  ...... 117 ▲         • isoprot 1mg  ...... 111 ▲         • isoprot 10mg  ...... 129 ▲▲           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — ECG parameters — unconscious         ECG   Maurer1 amplitude of P-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.0820         • atenolol 10mg  ...... 0.0800         • isoprot 1mg  ...... 0.100         • isoprot 10mg  ...... 0.103           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of Q-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.00400 ▲         • atenolol 10mg  ...... -0.00545 ▲         • isoprot 1mg  ...... -0.00444         • isoprot 10mg  ...... -0.00778           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of R-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.638         • atenolol 10mg  ...... 0.540         • isoprot 1mg  ...... 0.514         • isoprot 10mg  ...... 0.696           • comparison   23 strains   age 7-13wks   Inbred Maurer1 amplitude of S-wave [mV]     control and  atenolol, isoproterenol2wks       • control  ...... -0.213         • atenolol 10mg  ...... -0.146         • isoprot 1mg  ...... -0.286         • isoprot 10mg  ...... -0.154           • comparison   23 strains   age 7-13wks   Inbred Maurer1 duration P-wave [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 10.5 ▼         • atenolol 10mg  ...... 12.1         • isoprot 1mg  ...... 9.13 ▼         • isoprot 10mg  ...... 9.41 ▼           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval PR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 44.5         • atenolol 10mg  ...... 44.4         • isoprot 1mg  ...... 45.8 ▲▲         • isoprot 10mg  ...... 38.7           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval RR [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 116 ▼         • atenolol 10mg  ...... 144         • isoprot 1mg  ...... 110         • isoprot 10mg  ...... 103           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QRS [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 12.4         • atenolol 10mg  ...... 13.5         • isoprot 1mg  ...... 11.2         • isoprot 10mg  ...... 11.5           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval QT [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 54.6         • atenolol 10mg  ...... 57.8         • isoprot 1mg  ...... 46.3         • isoprot 10mg  ...... 46.2           • comparison   23 strains   age 7-13wks   Inbred Maurer1 interval ST [ms]     control and  atenolol, isoproterenol2wks       • control  ...... 42.2         • atenolol 10mg  ...... 44.3         • isoprot 1mg  ...... 35.0         • isoprot 10mg  ...... 34.9           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of P-wave [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 0.423         • atenolol 10mg  ...... 0.492         • isoprot 1mg  ...... 0.444         • isoprot 10mg  ...... 0.449           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QRS [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 1.81         • atenolol 10mg  ...... 1.74         • isoprot 1mg  ...... 0.883         • isoprot 10mg  ...... 1.85           • comparison   23 strains   age 7-13wks   Inbred Maurer1 area of QTc [ms*mV]     control and  atenolol, isoproterenol2wks       • control  ...... 50.7         • atenolol 10mg  ...... 48.1         • isoprot 1mg  ...... 44.2         • isoprot 10mg  ...... 45.2           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — conscious         tail cuff   Maurer1 pulse rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 729 ▲         • atenolol 10mg  ...... 588 ▲         • isoprot 1mg  ...... 821         • isoprot 10mg  ...... 790           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart rate — unconscious         ECG   Maurer1 heart rate [n/min]     control and  atenolol, isoproterenol2wks       • control  ...... 520 ▲         • atenolol 10mg  ...... 420         • isoprot 1mg  ...... 550         • isoprot 10mg  ...... 586 ▲           • comparison   23 strains   age 7-13wks   Inbred   cardiovascular — heart weight         scales   Maurer1 heart weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 82.6 ▼               • atenolol 10mg  ...... 82.2 ▼               • isoprot 1mg  ...... 87.5 ▼               • isoprot 10mg  ...... 110                 • comparison         normalized:             • control  ...... 4.19               • atenolol 10mg  ...... 4.06               • isoprot 1mg  ...... 4.32               • isoprot 10mg  ...... 4.88                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 4.31 ▼               • atenolol 10mg  ...... 4.65 ▼               • isoprot 1mg  ...... 5.67 ▼               • isoprot 10mg  ...... 7.49                 • comparison         normalized:             • control  ...... 0.219               • atenolol 10mg  ...... 0.230               • isoprot 1mg  ...... 0.280               • isoprot 10mg  ...... 0.332                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 ventricle (both) weight [mg]     control and  atenolol, isoproterenol2wks       weight:             • control  ...... 78.3 ▼               • atenolol 10mg  ...... 77.6 ▼               • isoprot 1mg  ...... 81.9 ▼               • isoprot 10mg  ...... 102                 • comparison         normalized:             • control  ...... 3.98               • atenolol 10mg  ...... 3.83               • isoprot 1mg  ...... 4.04               • isoprot 10mg  ...... 4.54                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol2wks       • control  ...... 18.2         • atenolol 10mg  ...... 16.7         • isoprot 1mg  ...... 14.5         • isoprot 10mg  ...... 13.7           • comparison   23 strains   age 7-13wks   Inbred

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