|
body weight
scales
|
|
|
fold change in body weight over testing period
[ratio]
control and
atenolol, isoproterenol
......
1.09
......
1.11
......
1.12
......
1.15
|
Inbred
|
| |
|
cardiovascular — blood pressure
tail cuff
|
|
|
systolic blood pressure
[mmHg]
control and
atenolol, isoproterenol
......
110
......
101
......
100
......
99.8
|
Inbred
|
| |
|
cardiovascular — ECG parameters — unconscious
ECG
|
|
|
amplitude of P-wave
[mV]
control and
atenolol, isoproterenol
......
0.109
......
0.0800
......
0.123
......
0.106
|
Inbred
|
|
|
amplitude of Q-wave
[mV]
control and
atenolol, isoproterenol
......
0.0150
......
-0.00778
......
0.00444
......
0
|
Inbred
|
|
|
amplitude of R-wave
[mV]
control and
atenolol, isoproterenol
......
0.601
......
0.528
......
0.546
......
0.553
|
Inbred
|
|
|
amplitude of S-wave
[mV]
control and
atenolol, isoproterenol
......
-0.170
......
-0.229
......
-0.170
......
-0.150
|
Inbred
|
|
|
duration P-wave
[ms]
control and
atenolol, isoproterenol
......
13.2
......
12.4
......
11.5
......
10.8
|
Inbred
|
|
|
interval PR
[ms]
control and
atenolol, isoproterenol
......
55.4
......
60.0
......
47.0
......
47.8
|
Inbred
|
|
|
interval RR
[ms]
control and
atenolol, isoproterenol
......
107
......
125
......
103
......
112
|
Inbred
|
|
|
interval QRS
[ms]
control and
atenolol, isoproterenol
......
14.6
......
13.4
......
12.4
......
11.7
|
Inbred
|
|
|
interval QT
[ms]
control and
atenolol, isoproterenol
......
47.9
......
56.9
......
45.5
......
43.0
|
Inbred
|
|
|
interval ST
[ms]
control and
atenolol, isoproterenol
......
33.2
......
43.5
......
33.2
......
31.0
|
Inbred
|
|
|
area of P-wave
[ms*mV]
control and
atenolol, isoproterenol
......
0.742
......
0.501
......
0.690
......
0.590
|
Inbred
|
|
|
area of QRS
[ms*mV]
control and
atenolol, isoproterenol
......
2.34
......
2.17
......
1.77
......
1.70
|
Inbred
|
|
|
area of QTc
[ms*mV]
control and
atenolol, isoproterenol
......
46.5
......
50.8
......
45.0
......
40.9
|
Inbred
|
| |
|
cardiovascular — heart rate — conscious
tail cuff
|
|
|
pulse rate
[n/min]
control and
atenolol, isoproterenol
......
557
......
478
......
782
......
817
|
Inbred
|
| |
|
cardiovascular — heart rate — unconscious
ECG
|
|
|
heart rate
[n/min]
control and
atenolol, isoproterenol
......
567
......
484
......
590
......
543
|
Inbred
|
| |
|
cardiovascular — heart weight
scales
|
|
|
heart weight
[mg]
control and
atenolol, isoproterenol
weight:
......
129
......
120
......
124
......
137
normalized:
......
4.66
......
4.64
......
4.74
......
5.20
|
Inbred
|
|
|
atria weight
[mg]
control and
atenolol, isoproterenol
weight:
......
7.36
......
7.18
......
7.38
......
8.71
normalized:
......
0.267
......
0.278
......
0.282
......
0.331
|
Inbred
|
|
|
ventricle (both) weight
[mg]
control and
atenolol, isoproterenol
weight:
......
121
......
113
......
117
......
128
normalized:
......
4.39
......
4.36
......
4.46
......
4.86
|
Inbred
|
|
|
atria weight to ventricle weight ratio
[ratio]
control and
atenolol, isoproterenol
......
16.6
......
15.8
......
15.9
......
14.8
|
Inbred
|