body weight         scales   Harrill2 fold change in body weight over testing period [ratio]     control and  DB289       • control  ...... 0.906         • DB289  ...... 0.802         • difference  ...... 0.885         34 strains   age 6-8wks   Inbred   brain — morphology — size         histopathology   Wahlsten1 corpus callosum         • length at mid-sagittal plane  ...... 3.83   3.86         • cross-sectional area at midplane  ...... 0.755   0.767         • index  ...... 0.991   0.970         21 strains   age 12wks   Inbred Wahlsten1 hippocampus         • length at mid-sagittal plane  ...... 1.41   1.34         • cross-sectional area at midplane  ...... 0.285   0.293         • index  ...... 1.10   1.09         21 strains   age 12wks   Inbred Wahlsten1 anterior commissure         • length at mid-sagittal plane  ...... 0.458   0.445         • cross-sectional area at midplane  ...... 0.122   0.129         • index  ...... 1.12   1.14         21 strains   age 12wks   Inbred   brain — morphology — weight         scales   Wahlsten1 brain weight (after fixation and trimming)         • weight  ...... 0.412   0.424         • as percent of body weight  ...... 2.21   1.86         21 strains   age 12wks   Inbred   cardiovascular — aorta and ventricle dimensions         echocardiography   Jaxpheno8 intra-ventricular septum thickness [mm]         • diastolic  ...... 0.707         • systolic  ...... 0.907           • comparison   6 strains   age 12wks   Inbred Jaxpheno8 left ventricle anterior wall thickness [mm]         • diastolic  ...... 0.732         • systolic  ...... 1.11           • comparison   6 strains   age 12wks   Inbred Jaxpheno8 left ventricle posterior wall thickness [mm]         • diastolic  ...... 0.670         • systolic  ...... 1.02           • comparison   6 strains   age 12wks   Inbred Jaxpheno8 left ventricle internal dimension [mm]         • diastolic  ...... 3.44 ▼         • systolic  ...... 2.06 ▼           • comparison   6 strains   age 12wks   Inbred Jaxpheno8 left ventricle volume [µL]         • diastolic  ...... 49.7 ▼         • systolic  ...... 14.2 ▼           • comparison   6 strains   age 12wks   Inbred   cardiovascular — heart weight         scales   Deschepper1 ventricle weight [mg]         weight:             • both  ...... 69.9 ▼   83.4               • left  ...... 53.8 ▼   62.9               • right  ...... 16.2   20.4         normalized:             • both  ...... 3.98   3.55 ▼               • left  ...... 3.05 ▼   2.67 ▼               • right  ...... 0.922   0.865               13 strains   age 10wks   Inbred Deschepper1 atria weight [mg]         weight:             • both  ...... 5.81   5.81               • left  ...... 3.00   3.11               • right  ...... 2.81   2.70         normalized:             • both  ...... 0.330   0.250               • left  ...... 0.170 ▲   0.135               • right  ...... 0.159   0.115               13 strains   age 10wks   Inbred Maurer1 heart weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 77.3 ▼               • atenolol 10mg  ...... 69.6 ▼               • isoprot 1mg  ...... 80.5 ▼               • isoprot 10mg  ...... 95.6 ▼                 • comparison         normalized:             • control  ...... 3.72 ▼               • atenolol 10mg  ...... 3.84 ▼               • isoprot 1mg  ...... 4.16               • isoprot 10mg  ...... 4.96                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 4.53 ▼               • atenolol 10mg  ...... 4.25 ▼               • isoprot 1mg  ...... 5.20 ▼               • isoprot 10mg  ...... 6.14 ▼                 • comparison         normalized:             • control  ...... 0.216               • atenolol 10mg  ...... 0.233               • isoprot 1mg  ...... 0.273               • isoprot 10mg  ...... 0.317                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 ventricle (both) weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 72.7 ▼               • atenolol 10mg  ...... 65.4 ▼               • isoprot 1mg  ...... 75.3 ▼               • isoprot 10mg  ...... 89.5 ▼                 • comparison         normalized:             • control  ...... 3.51 ▼               • atenolol 10mg  ...... 3.61 ▼               • isoprot 1mg  ...... 3.89               • isoprot 10mg  ...... 4.64                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol 2wks       • control  ...... 16.3         • atenolol 10mg  ...... 15.6         • isoprot 1mg  ...... 14.6         • isoprot 10mg  ...... 14.8           • comparison   23 strains   age 7-13wks   Inbred Reed1 heart weight         • weight [g]  ...... 0.112 ▼         • as percent of body weight [%]  ...... 0.451         28 strains   age 29-67wks   Inbred   endocrine — adrenal — morphology — weight         scales   Deschepper1 adrenal weight [mg]         weight:             • both  ...... 5.26   4.30               • left  ...... 2.73   1.99               • right  ...... 2.83   2.31         normalized:             • both  ...... 0.301   0.185               • left  ...... 0.156   0.0857               • right  ...... 0.162   0.0995               13 strains   age 10wks   Inbred   eye — morphology         metric   Chang1 eye diameter   [mm] ...... 3.24   17 strains   age >7wks   Inbred   immune system — morphology — thymus         scales   Deschepper1 thymus weight [mg]         • weight  ...... 41.8   36.3         • normalized  ...... 2.38   1.55         13 strains   age 10wks   Inbred   kidney — morphology — weight         scales   Deschepper1 kidney weight [mg]         weight:             • both  ...... 228 ▼   310               • left  ...... 111 ▼   153               • right  ...... 116 ▼   157         normalized:             • both  ...... 12.9   13.1               • left  ...... 6.30   6.50               • right  ...... 6.61   6.64 ▼               13 strains   age 10wks   Inbred Harrill2 kidney (left) weight [g]     control and  DB289       • control  ...... 0.120         • DB289  ...... 0.100           • comparison   34 strains   age 6-8wks   Inbred Harrill2 kidney (right) weight [g]     control and  DB289       • control  ...... 0.114         • DB289  ...... 0.102           • comparison   34 strains   age 6-8wks   Inbred Harrill2 kidney (both) weight [g]     control and  DB289       • control  ...... 0.232         • DB289  ...... 0.202           • comparison   34 strains   age 6-8wks   Inbred Harrill2 total kidney weight as percent of body weight [%]     control and  DB289       • control  ...... 1.31         • DB289  ...... 1.26         • difference  ...... 0.962         34 strains   age 6-8wks   Inbred Reed1 kidney weight         • weight [g]  ...... 0.392 ▼         • as percent of body weight [%]  ...... 1.59 ▼         28 strains   age 29-67wks   Inbred   liver — weight         scales   Harrill2 liver weight at sacrifice [g]     control and  DB289       • control  ...... 0.686         • DB289  ...... 0.514           • comparison   34 strains   age 6-8wks   Inbred Harrill2 liver weight as percent of body weight [%]     control and  DB289       • control  ...... 3.85         • DB289  ...... 3.24         • difference  ...... 0.842         34 strains   age 6-8wks   Inbred Paigen1 liver weight at sacrifice   [g] ...... 2.40 ▲   2.21     high-fat diet   8wks 43 strains   age 15-19wks   Inbred Threadgill1 liver weight [g]     control and  acetaminophen       • control  ...... 1.03 (N=4)         24h post-Rx mg/kg:             • 100  ......             • 200  ......             • 300  ...... 0.997 (N=4)                 • comparison   37 strains   age 8-17wks   Inbred   local experiment parameter   Rusyn2 liver weight as percent of body weight, naive   [ratio] ...... 17 strains   age 7wks   Inbred   reproduction — morphology — male         scales   Handel1 seminal vesicle weight (both left and right)   [g] ...... 0.149   14 strains   age 8-10wks   Inbred Handel1 testicular weight (both left and right)   [g] ...... 0.150   14 strains   age 8-10wks   Inbred

105 measurements listed.