|
body weight
scales
|
|
|
|
fold change in body weight over testing period
[ratio]
| control and
|
DB289
|
|
......
0.890
......
0.810
......
0.910
|
Inbred
|
| |
|
brain — morphology — size
histopathology
|
|
|
......
2.27
2.98
......
0.582
0.763
......
0.623
0.813
|
Inbred
|
|
|
......
1.44
1.52
......
0.295
0.293
......
0.917
0.905
|
Inbred
|
|
|
......
0.442
0.402
......
0.118
0.107
......
0.888
0.807
|
Inbred
|
| |
|
brain — morphology — weight
scales
|
|
|
|
brain weight (after fixation and trimming)
|
|
......
0.486
0.483
......
2.31
1.89
|
Inbred
|
| |
|
cardiovascular — heart weight
scales
|
|
|
weight:
......
80.4
107
......
64.4
86.6
......
16.0
20.5
normalized:
......
4.51
4.72
......
3.61
3.81
......
0.898
0.904
|
Inbred
|
|
|
weight:
......
2.43
4.70
......
0.922
2.30
......
1.51
2.40
normalized:
......
0.137
0.205
......
0.0519
0.100
......
0.0851
0.104
|
Inbred
|
|
|
weight:
......
96.4
......
99.0
......
116
......
153
normalized:
......
4.68
......
4.66
......
4.95
......
6.25
|
Inbred
|
|
|
weight:
......
3.95
......
4.61
......
5.31
......
7.05
normalized:
......
0.191
......
0.216
......
0.229
......
0.289
|
Inbred
|
|
|
weight:
......
92.5
......
94.4
......
110
......
146
normalized:
......
4.49
......
4.44
......
4.72
......
5.97
|
Inbred
|
|
|
......
24.9
......
20.8
......
21.8
......
20.9
|
Inbred
|
| |
|
endocrine — adrenal — morphology — weight
scales
|
|
|
weight:
......
4.26
3.48
......
2.56
1.90
......
2.00
1.58
normalized:
......
0.240
0.151
......
0.144
0.0827
......
0.113
0.0686
|
Inbred
|
| |
|
immune system — morphology — thymus
scales
|
|
|
......
38.6
37.5
......
2.15
1.65
|
Inbred
|
| |
|
kidney — morphology — area
metric
|
|
|
|
kidney planar surface area
[mm2]
|
|
......
5.64
5.57
......
4.95
4.69
|
Inbred
|
|
|
|
normalized kidney planar surface area
[mm2/g]
|
|
......
3.52
3.39
......
3.09
2.86
|
Inbred
|
| |
|
kidney — morphology — weight
scales
|
|
|
weight:
......
234
360
......
115
174
......
119
183
normalized:
......
13.2
15.6
......
6.47
7.65
......
6.69
7.90
|
Inbred
|
|
|
......
0.00762
0.00711
......
0.00786
0.00720
......
0.0155
0.0143
|
Inbred
|
|
|
|
percent kidney weight to body weight
[%]
|
|
......
0.475
0.432
......
0.490
0.436
......
0.965
0.868
|
Inbred
|
|
|
|
kidney (left) weight
[g]
| control and
|
DB289
|
|
......
0.112
......
0.104
|
Inbred
|
|
|
|
kidney (right) weight
[g]
| control and
|
DB289
|
|
......
0.120
......
0.106
|
Inbred
|
|
|
|
kidney (both) weight
[g]
| control and
|
DB289
|
|
......
0.234
......
0.208
|
Inbred
|
|
|
|
total kidney weight as percent of body weight
[%]
| control and
|
DB289
|
|
......
1.32
......
1.27
......
0.962
|
Inbred
|
| |
|
liver — weight
scales
|
|
|
|
liver weight at sacrifice
[g]
| control and
|
DB289
|
|
......
0.596
......
0.470
|
Inbred
|
|
|
|
liver weight as percent of body weight
[%]
| control and
|
DB289
|
|
......
3.37
......
2.88
......
0.855
|
Inbred
|
|
|
|
Inbred
|
|
|
|
liver weight as a percent of body weight
[%]
|
high-fat diet, ethanol
|
|
......
5.48
(N=3)
......
7.96
(N=3)
|
Inbred
|
|
|
......
0.984
24h post-Rx mg/kg:
......
......
......
1.00
(N=4)
|
Inbred
|
| |
|
local experiment parameter
|
|
|
|
Inbred
|
| |
|
reproduction — morphology — male
scales
|
|
|
|
Inbred
|
|
|
|
Inbred
|