body weight         scales   Harrill2 fold change in body weight over testing period [ratio]     control and  DB289       • control  ...... 0.892         • DB289  ...... 0.880 ▲         • difference  ...... 0.987 ▲         34 strains   age 6-8wks   Inbred   brain — morphology — size         histopathology   Wahlsten1 corpus callosum         • length at mid-sagittal plane  ...... 3.96   4.02         • cross-sectional area at midplane  ...... 0.804   0.795         • index  ...... 1.01   0.952         21 strains   age 12wks   Inbred Wahlsten1 hippocampus         • length at mid-sagittal plane  ...... 1.87 ▲   1.82 ▲         • cross-sectional area at midplane  ...... 0.342   0.351         • index  ...... 1.27 ▲   1.24 ▲         21 strains   age 12wks   Inbred Wahlsten1 anterior commissure         • length at mid-sagittal plane  ...... 0.394 ▼   0.401         • cross-sectional area at midplane  ...... 0.107   0.113         • index  ...... 0.944   0.958         21 strains   age 12wks   Inbred   brain — morphology — weight         scales   Wahlsten1 brain weight (after fixation and trimming)         • weight  ...... 0.425   0.440         • as percent of body weight  ...... 2.18   1.81         21 strains   age 12wks   Inbred   cardiovascular — heart weight         scales   Deschepper1 ventricle weight [mg]         weight:             • both  ...... 79.9   85.0               • left  ...... 62.0   67.2               • right  ...... 17.9   17.8         normalized:             • both  ...... 4.27   3.99               • left  ...... 3.32   3.15               • right  ...... 0.948   0.832               13 strains   age 10wks   Inbred Deschepper1 atria weight [mg]         weight:             • both  ...... 6.67   2.94 ▼               • left  ...... 2.43   1.51 ▼               • right  ...... 4.23 ▲   1.43 ▼         normalized:             • both  ...... 0.356   0.138 ▼               • left  ...... 0.130   0.0711 ▼               • right  ...... 0.226 ▲   0.0672 ▼               13 strains   age 10wks   Inbred Maurer1 heart weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 92.5               • atenolol 10mg  ...... 91.7               • isoprot 1mg  ...... 100               • isoprot 10mg  ...... 112                 • comparison         normalized:             • control  ...... 4.16               • atenolol 10mg  ...... 4.18               • isoprot 1mg  ...... 4.16               • isoprot 10mg  ...... 4.52                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 5.71               • atenolol 10mg  ...... 5.88               • isoprot 1mg  ...... 7.30               • isoprot 10mg  ...... 7.79                 • comparison         normalized:             • control  ...... 0.257               • atenolol 10mg  ...... 0.268               • isoprot 1mg  ...... 0.302               • isoprot 10mg  ...... 0.315                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 ventricle (both) weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 86.9               • atenolol 10mg  ...... 85.8               • isoprot 1mg  ...... 93.0               • isoprot 10mg  ...... 104                 • comparison         normalized:             • control  ...... 3.91               • atenolol 10mg  ...... 3.91               • isoprot 1mg  ...... 3.85               • isoprot 10mg  ...... 4.21                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol 2wks       • control  ...... 15.4         • atenolol 10mg  ...... 14.8         • isoprot 1mg  ...... 12.9 ▼         • isoprot 10mg  ...... 13.4           • comparison   23 strains   age 7-13wks   Inbred Reed1 heart weight         • weight [g]  ...... 0.125 ▼         • as percent of body weight [%]  ...... 0.438 ▼         28 strains   age 29-67wks   Inbred   endocrine — adrenal — morphology — weight         scales   Deschepper1 adrenal weight [mg]         weight:             • both  ...... 5.31   2.94 ▼               • left  ...... 2.84   1.51 ▼               • right  ...... 2.47   1.43         normalized:             • both  ...... 0.287   0.138               • left  ...... 0.152   0.0711 ▼               • right  ...... 0.135   0.0672               13 strains   age 10wks   Inbred   immune system — morphology — thymus         scales   Deschepper1 thymus weight [mg]         • weight  ...... 43.8   44.9         • normalized  ...... 2.36   2.10         13 strains   age 10wks   Inbred   kidney — morphology — area         metric   Gupta1 kidney planar surface area [mm2]         • left  ...... 4.66 (N=2) ▼   5.60 (N=3)         • right  ...... 6.06 (N=2) ▲▲   5.81 (N=3) ▲           • comparison   8 strains   age postnatal d1   Inbred Gupta1 normalized kidney planar surface area [mm2/g]         • left  ...... 3.27 (N=2) ▼   3.93 (N=3)         • right  ...... 4.24 (N=2) ▲   4.07 (N=3) ▲           • comparison   7 strains   age postnatal d1   Inbred   kidney — morphology — weight         scales   Deschepper1 kidney weight [mg]         weight:             • both  ...... 273   327               • left  ...... 131   160               • right  ...... 142   167         normalized:             • both  ...... 14.7   15.4               • left  ...... 7.04   7.51               • right  ...... 7.66   7.85               13 strains   age 10wks   Inbred Gupta1 kidney weight [g]         • left  ...... 0.00700 (N=2)   0.00663 (N=3)         • right  ...... 0.00870 (N=2) ▲   0.00840 (N=3) ▲         • both  ...... 0.0157 (N=2) ▲   0.0150 (N=3) ▲           • comparison   7 strains   age postnatal d1   Inbred Gupta1 percent kidney weight to body weight [%]         • left  ...... 0.492 (N=2)   0.466 (N=3)         • right  ...... 0.609 (N=2) ▲▲   0.589 (N=3) ▲         • both  ...... 1.10 (N=2) ▲   1.05 (N=3)           • comparison   7 strains   age postnatal d1   Inbred Harrill2 kidney (left) weight [g]     control and  DB289       • control  ...... 0.133 (N=4)         • DB289  ...... 0.116           • comparison   34 strains   age 6-8wks   Inbred Harrill2 kidney (right) weight [g]     control and  DB289       • control  ...... 0.166 ▲         • DB289  ...... 0.126           • comparison   34 strains   age 6-8wks   Inbred Harrill2 kidney (both) weight [g]     control and  DB289       • control  ...... 0.280 (N=4)         • DB289  ...... 0.250           • comparison   34 strains   age 6-8wks   Inbred Harrill2 total kidney weight as percent of body weight [%]     control and  DB289       • control  ...... 1.65 (N=4)         • DB289  ...... 1.48         • difference  ...... 0.897         34 strains   age 6-8wks   Inbred Reed1 kidney weight         • weight [g]  ...... 0.569         • as percent of body weight [%]  ...... 2.00         28 strains   age 29-67wks   Inbred   liver — weight         scales   Harrill2 liver weight at sacrifice [g]     control and  DB289       • control  ...... 0.732         • DB289  ...... 0.700           • comparison   34 strains   age 6-8wks   Inbred Harrill2 liver weight as percent of body weight [%]     control and  DB289       • control  ...... 4.26         • DB289  ...... 4.17 ▲         • difference  ...... 0.979 ▲         34 strains   age 6-8wks   Inbred Paigen1 liver weight at sacrifice   [g] ...... 1.62   1.78     high-fat diet   8wks 43 strains   age 15-19wks   Inbred Threadgill1 liver weight [g]     control and  acetaminophen       • control  ...... 1.18 (N=4)         24h post-Rx mg/kg:             • 100  ......             • 200  ......             • 300  ...... 1.18 (N=4)                 • comparison   37 strains   age 8-17wks   Inbred

101 measurements listed.