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MPD - Phenotype data: orgmetric organ metrics
Measurements:


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AKR/J
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body weight         scales  
Harrill2
fold change in body weight over testing period [ratio]     control and  DB289
      • control  ...... 0.888  
      • DB289  ...... 0.690  
      • difference  ...... 0.777  
     
34 strains   age 6-8wks
  Inbred
 
brain — morphology — size         histopathology  
Wahlsten1
corpus callosum  
      • length at mid-sagittal plane  ...... 3.77   3.69  
      • cross-sectional area at midplane  ...... 0.926   0.921  
      • index  ...... 0.960   0.993  
     
21 strains   age 12wks
  Inbred
Wahlsten1
hippocampus  
      • length at mid-sagittal plane  ...... 1.53   1.47  
      • cross-sectional area at midplane  ...... 0.303   0.288  
      • index  ...... 0.911   0.903  
     
21 strains   age 12wks
  Inbred
Wahlsten1
anterior commissure  
      • length at mid-sagittal plane  ...... 0.459   0.446  
      • cross-sectional area at midplane  ...... 0.122   0.120  
      • index  ...... 0.905   0.923  
     
21 strains   age 12wks
  Inbred
 
brain — morphology — weight         scales  
Wahlsten1
brain weight (after fixation and trimming)  
      • weight  ...... 0.491   0.477  
      • as percent of body weight  ...... 1.97   1.70  
     
21 strains   age 12wks
  Inbred
 
cardiovascular — aorta and ventricle dimensions         echocardiography  
Jaxpheno8
intra-ventricular septum thickness [mm]  
      • diastolic  ...... 0.817  
      • systolic  ...... 1.18  
        • comparison  
6 strains   age 12wks
  Inbred
Jaxpheno8
left ventricle anterior wall thickness [mm]  
      • diastolic  ...... 0.853  
      • systolic  ...... 1.25  
        • comparison  
6 strains   age 12wks
  Inbred
Jaxpheno8
left ventricle posterior wall thickness [mm]  
      • diastolic  ...... 0.760  
      • systolic  ...... 1.06  
        • comparison  
6 strains   age 12wks
  Inbred
Jaxpheno8
left ventricle internal dimension [mm]  
      • diastolic  ...... 3.92  
      • systolic  ...... 2.51  
        • comparison  
6 strains   age 12wks
  Inbred
Jaxpheno8
left ventricle volume [µL]  
      • diastolic  ...... 66.8  
      • systolic  ...... 22.8  
        • comparison  
6 strains   age 12wks
  Inbred
 
cardiovascular — heart weight         scales  
Deschepper1
ventricle weight [mg]  
      weight:
            • both  ...... 112   130  
            • left  ...... 86.4   97.7  
            • right  ...... 27.9   32.4  
      normalized:
            • both  ...... 4.27   4.71  
            • left  ...... 3.30   3.54  
            • right  ...... 1.07   1.17  
           
13 strains   age 10wks
  Inbred
Deschepper1
atria weight [mg]  
      weight:
            • both  ...... 6.09   4.80  
            • left  ...... 2.52   2.39  
            • right  ...... 3.57   2.36  
      normalized:
            • both  ...... 0.228   0.172  
            • left  ...... 0.0939   0.0858  
            • right  ...... 0.134   0.0854  
           
13 strains   age 10wks
  Inbred
Maurer1
heart weight [mg]     control and  atenolol, isoproterenol
      weight:
            • control  ...... 125  
            • atenolol 10mg  ...... 120  
            • isoprot 1mg  ...... 129  
            • isoprot 10mg  ...... 133  
              • comparison  
      normalized:
            • control  ...... 4.56  
            • atenolol 10mg  ...... 4.27  
            • isoprot 1mg  ...... 4.45  
            • isoprot 10mg  ...... 4.76  
              • comparison  
23 strains   age 7-13wks
  Inbred
Maurer1
atria weight [mg]     control and  atenolol, isoproterenol
      weight:
            • control  ...... 5.58  
            • atenolol 10mg  ...... 5.56  
            • isoprot 1mg  ...... 6.79  
            • isoprot 10mg  ...... 7.64  
              • comparison  
      normalized:
            • control  ...... 0.203  
            • atenolol 10mg  ...... 0.198  
            • isoprot 1mg  ...... 0.233  
            • isoprot 10mg  ...... 0.272  
              • comparison  
23 strains   age 7-13wks
  Inbred
Maurer1
ventricle (both) weight [mg]     control and  atenolol, isoproterenol
      weight:
            • control  ...... 120  
            • atenolol 10mg  ...... 114  
            • isoprot 1mg  ...... 122  
            • isoprot 10mg  ...... 125  
              • comparison  
      normalized:
            • control  ...... 4.36  
            • atenolol 10mg  ...... 4.07  
            • isoprot 1mg  ...... 4.22  
            • isoprot 10mg  ...... 4.48  
              • comparison  
23 strains   age 7-13wks
  Inbred
Maurer1
atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol
      • control  ...... 21.5  
      • atenolol 10mg  ...... 20.7  
      • isoprot 1mg  ...... 18.2  
      • isoprot 10mg  ...... 16.7  
        • comparison  
23 strains   age 7-13wks
  Inbred
Reed1
heart weight  
      • weight [g]  ...... 0.173  
      • as percent of body weight [%]  ...... 0.503  
     
28 strains   age 29-67wks
  Inbred
 
endocrine — adrenal — morphology — weight         scales  
Deschepper1
adrenal weight [mg]  
      weight:
            • both  ...... 6.63   3.62  
            • left  ...... 3.29   1.93  
            • right  ...... 3.33   1.69  
      normalized:
            • both  ...... 0.242   0.132  
            • left  ...... 0.121   0.0702  
            • right  ...... 0.125   0.0615  
           
13 strains   age 10wks
  Inbred
 
immune system — morphology — thymus         scales  
Deschepper1
thymus weight [mg]  
      • weight  ...... 117 ▲▲   66.0  
      • normalized  ...... 4.42 ▲▲   2.39  
     
13 strains   age 10wks
  Inbred
 
kidney — morphology — area         metric  
Gupta1
kidney planar surface area [mm2]  
      • left  ...... 5.03 (N=4)   5.76  
      • right  ...... 4.48 (N=4)   5.17  
        • comparison  
8 strains   age postnatal d1
  Inbred
Gupta1
normalized kidney planar surface area [mm2/g]  
      • left  ...... 3.77 (N=4)   3.97  
      • right  ...... 3.35 (N=4)   3.57  
        • comparison  
7 strains   age postnatal d1
  Inbred
 
kidney — morphology — weight         scales  
Deschepper1
kidney weight [mg]  
      weight:
            • both  ...... 309   399  
            • left  ...... 150   193  
            • right  ...... 159   206  
      normalized:
            • both  ...... 11.7   14.5  
            • left  ...... 5.73   7.01  
            • right  ...... 6.01   7.48  
           
13 strains   age 10wks
  Inbred
Gupta1
kidney weight [g]  
      • left  ...... 0.00690 (N=4)   0.00730  
      • right  ...... 0.00705 (N=4)   0.00785  
      • both  ...... 0.0140 (N=4)   0.0151  
        • comparison  
7 strains   age postnatal d1
  Inbred
Gupta1
percent kidney weight to body weight [%]  
      • left  ...... 0.514 (N=4)   0.502  
      • right  ...... 0.523 (N=4)   0.540  
      • both  ...... 1.04 (N=4)   1.04  
        • comparison  
7 strains   age postnatal d1
  Inbred
Harrill2
kidney (left) weight [g]     control and  DB289
      • control  ...... 0.138  
      • DB289  ...... 0.114  
        • comparison  
34 strains   age 6-8wks
  Inbred
Harrill2
kidney (right) weight [g]     control and  DB289
      • control  ...... 0.148  
      • DB289  ...... 0.120  
        • comparison  
34 strains   age 6-8wks
  Inbred
Harrill2
kidney (both) weight [g]     control and  DB289
      • control  ...... 0.288  
      • DB289  ...... 0.234  
        • comparison  
34 strains   age 6-8wks
  Inbred
Harrill2
total kidney weight as percent of body weight [%]     control and  DB289
      • control  ...... 1.38  
      • DB289  ...... 1.48  
      • difference  ...... 1.07  
     
34 strains   age 6-8wks
  Inbred
Reed1
kidney weight  
      • weight [g]  ...... 0.562  
      • as percent of body weight [%]  ...... 1.63  
     
28 strains   age 29-67wks
  Inbred
 
liver — weight         scales  
Harrill2
liver weight at sacrifice [g]     control and  DB289
      • control  ...... 0.882  
      • DB289  ...... 0.612  
        • comparison  
34 strains   age 6-8wks
  Inbred
Harrill2
liver weight as percent of body weight [%]     control and  DB289
      • control  ...... 4.26  
      • DB289  ...... 3.88  
      • difference  ...... 0.911  
     
34 strains   age 6-8wks
  Inbred
Paigen1
liver weight at sacrifice   [g] ...... 2.42   2.53     high-fat diet 8wks 43 strains   age 15-19wks
  Inbred
Rusyn5
liver weight as a percent of body weight [%]   high-fat diet , ethanol
      • high-fat only  ...... 6.88 (N=3)  
      • high-fat and ethanol  ...... 7.02 (N=3)  
        • comparison  
14 strains   age 8-14wks
  Inbred
Threadgill1
liver weight [g]     control and  acetaminophen
      • control  ...... 1.44 (N=4)  
      24h post-Rx mg/kg:
            • 100  ......
            • 200  ......
            • 300  ...... 1.67  
              • comparison  
37 strains   age 8-17wks
  Inbred
 
local experiment parameter  
Rusyn2
liver weight as percent of body weight, naive   [ratio] ...... 17 strains   age 7wks
  Inbred
 
reproduction — morphology — male         scales  
Handel1
seminal vesicle weight (both left and right)   [g] ...... 0.169   14 strains   age 8-10wks
  Inbred
Handel1
testicular weight (both left and right)   [g] ...... 0.110   14 strains   age 8-10wks
  Inbred


116 measurements listed.

 


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