Home       About             Help       Phenotype data > NOD/ShiLtJ strain > organ metrics Measurements: About these NOD/ShiLtJ averages (♀ ♂) Exit NOD/ShiLtJ mode body weight         scales   Harrill2 fold change in body weight over testing period [ratio]     control and  DB289       • control  ...... 0.874         • DB289  ...... 0.792         • difference  ...... 0.906         34 strains   age 6-8wks   Inbred   brain — morphology — size         histopathology   Wahlsten1 corpus callosum         • length at mid-sagittal plane  ...... 4.02   3.96         • cross-sectional area at midplane  ...... 1.16 ▲   1.09 ▲         • index  ...... 1.02   0.998         21 strains   age 12wks   Inbred Wahlsten1 hippocampus         • length at mid-sagittal plane  ...... 1.82   1.75         • cross-sectional area at midplane  ...... 0.422 ▲   0.410 ▲         • index  ...... 1.07   1.08         21 strains   age 12wks   Inbred Wahlsten1 anterior commissure         • length at mid-sagittal plane  ...... 0.504 ▲   0.476         • cross-sectional area at midplane  ...... 0.148 ▲   0.149 ▲         • index  ...... 0.941   0.988         21 strains   age 12wks   Inbred   brain — morphology — weight         scales   Jaxpheno2 brain weight [g]         • age 8wks  ...... 0.475 ▲   0.458 ▲         • age 16wks  ...... 0.471 ▲   0.480 ▲           • age comparison   11 strains   ages shown   Inbred Jaxpheno2 brain weight as percent of body weight [%]         • age 8wks  ...... 2.26 ▲   1.78         • age 16wks  ...... 2.03 ▲   1.63 ▲           • age comparison   11 strains   ages shown   Inbred Wahlsten1 brain weight (after fixation and trimming)         • weight  ...... 0.558 ▲▲   0.540 ▲         • as percent of body weight  ...... 2.46   2.04         21 strains   age 12wks   Inbred   cardiovascular — heart weight         scales   Jaxpheno2 heart weight [g]         • age 8wks  ...... 0.131   0.139         • age 16wks  ...... 0.137   0.163           • age comparison   11 strains   ages shown   Inbred Jaxpheno2 heart weight as percent of body weight [%]         • age 8wks  ...... 0.626   0.546         • age 16wks  ...... 0.581   0.554           • age comparison   11 strains   ages shown   Inbred Maurer1 heart weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 103               • atenolol 10mg  ...... 99.5               • isoprot 1mg  ...... 110               • isoprot 10mg  ...... 125                 • comparison         normalized:             • control  ...... 4.02               • atenolol 10mg  ...... 3.92               • isoprot 1mg  ...... 4.19               • isoprot 10mg  ...... 4.80                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 5.40               • atenolol 10mg  ...... 6.50               • isoprot 1mg  ...... 7.18               • isoprot 10mg  ...... 8.42                 • comparison         normalized:             • control  ...... 0.211               • atenolol 10mg  ...... 0.255               • isoprot 1mg  ...... 0.273               • isoprot 10mg  ...... 0.324                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 ventricle (both) weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 97.2               • atenolol 10mg  ...... 93.0               • isoprot 1mg  ...... 103               • isoprot 10mg  ...... 116                 • comparison         normalized:             • control  ...... 3.81               • atenolol 10mg  ...... 3.67               • isoprot 1mg  ...... 3.92               • isoprot 10mg  ...... 4.48                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol 2wks       • control  ...... 18.2         • atenolol 10mg  ...... 14.6         • isoprot 1mg  ...... 14.4         • isoprot 10mg  ...... 13.8           • comparison   23 strains   age 7-13wks   Inbred Reed1 heart weight         • weight [g]  ...... 0.151         • as percent of body weight [%]  ...... 0.467         28 strains   age 29-67wks   Inbred   kidney — morphology — weight         scales   Harrill2 kidney (left) weight [g]     control and  DB289       • control  ...... 0.120         • DB289  ...... 0.106           • comparison   34 strains   age 6-8wks   Inbred Harrill2 kidney (right) weight [g]     control and  DB289       • control  ...... 0.114         • DB289  ...... 0.106           • comparison   34 strains   age 6-8wks   Inbred Harrill2 kidney (both) weight [g]     control and  DB289       • control  ...... 0.232         • DB289  ...... 0.210           • comparison   34 strains   age 6-8wks   Inbred Harrill2 total kidney weight as percent of body weight [%]     control and  DB289       • control  ...... 1.35         • DB289  ...... 1.37         • difference  ...... 1.01         34 strains   age 6-8wks   Inbred Jaxpheno2 kidney (left) weight [g]         • age 8wks  ...... 0.117   0.190         • age 16wks  ...... 0.160 ▲   0.248           • age comparison   11 strains   ages shown   Inbred Jaxpheno2 kidney (right) weight [g]         • age 8wks  ...... 0.125   0.177         • age 16wks  ...... 0.163 ▲   0.258           • age comparison   11 strains   ages shown   Inbred Jaxpheno2 kidney (left) weight, as percent of body weight [%]         • age 8wks  ...... 0.552   0.732         • age 16wks  ...... 0.692 ▲   0.839           • age comparison   11 strains   ages shown   Inbred Jaxpheno2 kidney (right) weight, as percent of body weight [%]         • age 8wks  ...... 0.591   0.680         • age 16wks  ...... 0.710 ▲   0.872           • age comparison   11 strains   ages shown   Inbred Reed1 kidney weight         • weight [g]  ...... 0.562         • as percent of body weight [%]  ...... 1.74         28 strains   age 29-67wks   Inbred   liver — weight         scales   Harrill2 liver weight at sacrifice [g]     control and  DB289       • control  ...... 0.704         • DB289  ...... 0.486           • comparison   34 strains   age 6-8wks   Inbred Harrill2 liver weight as percent of body weight [%]     control and  DB289       • control  ...... 4.09         • DB289  ...... 3.17 ▼         • difference  ...... 0.775 ▼         34 strains   age 6-8wks   Inbred Jaxpheno2 liver weight [g]         • age 8wks  ...... 1.11   1.33         • age 16wks  ...... 1.30   1.69 ▲           • age comparison   11 strains   ages shown   Inbred Jaxpheno2 liver weight as percent of body weight [%]         • age 8wks  ...... 5.30   5.13         • age 16wks  ...... 5.55 ▲   5.71 ▲▲           • age comparison   11 strains   ages shown   Inbred Paigen1 liver weight at sacrifice   [g] ...... 2.36 ▲   2.66 ▲     high-fat diet   8wks 43 strains   age 15-19wks   Inbred Threadgill1 liver weight [g]     control and  acetaminophen       • control  ...... 1.43 (N=4)         24h post-Rx mg/kg:             • 100  ...... 1.67 (N=4) ▲               • 200  ...... 1.63 (N=3) ▲               • 300  ...... 1.34 (N=4)                 • comparison   37 strains   age 8-17wks   Inbred   local experiment parameter   Rusyn2 liver weight as percent of body weight, naive   [ratio] ...... 8.37 (N=3) ▲▲   17 strains   age 7wks   Inbred   reproduction — morphology — male         scales   Handel1 seminal vesicle weight (both left and right)   [g] ...... 0.293 ▲   14 strains   age 8-10wks   Inbred Handel1 testicular weight (both left and right)   [g] ...... 0.186   14 strains   age 8-10wks   Inbred   spleen — weight         scales   Jaxpheno2 spleen weight [g]         • age 8wks  ...... 0.0743   0.0705         • age 16wks  ...... 0.0843   0.0852           • age comparison   11 strains   ages shown   Inbred Jaxpheno2 spleen weight, as percent of body weight [%]         • age 8wks  ...... 0.354   0.270         • age 16wks  ...... 0.351   0.288           • age comparison   11 strains   ages shown   Inbred

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