Home       About             Help       Phenotype data > SWR/J strain > organ metrics Measurements: About these SWR/J averages (♀ ♂) Exit SWR/J mode body weight         scales   Harrill2 fold change in body weight over testing period [ratio]     control and  DB289       • control  ...... 0.910         • DB289  ...... 0.785 (N=4)         • difference  ...... 0.863         34 strains   age 6-8wks   Inbred   brain — morphology — size         histopathology   Wahlsten1 corpus callosum         • length at mid-sagittal plane  ...... 4.04   4.06         • cross-sectional area at midplane  ...... 0.892   0.858         • index  ...... 1.07   1.04         21 strains   age 12wks   Inbred Wahlsten1 hippocampus         • length at mid-sagittal plane  ...... 1.74   1.69         • cross-sectional area at midplane  ...... 0.333   0.309         • index  ...... 1.17 ▲   1.10         21 strains   age 12wks   Inbred Wahlsten1 anterior commissure         • length at mid-sagittal plane  ...... 0.442   0.419         • cross-sectional area at midplane  ...... 0.126   0.116         • index  ...... 1.06   0.993         21 strains   age 12wks   Inbred   brain — morphology — weight         scales   Wahlsten1 brain weight (after fixation and trimming)         • weight  ...... 0.442   0.436         • as percent of body weight  ...... 2.40   1.90         21 strains   age 12wks   Inbred   cardiovascular — heart weight         scales   Maurer1 heart weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 82.6 ▼               • atenolol 10mg  ...... 82.2 ▼               • isoprot 1mg  ...... 87.5 ▼               • isoprot 10mg  ...... 110                 • comparison         normalized:             • control  ...... 4.19               • atenolol 10mg  ...... 4.06               • isoprot 1mg  ...... 4.32               • isoprot 10mg  ...... 4.88                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 4.31 ▼               • atenolol 10mg  ...... 4.65 ▼               • isoprot 1mg  ...... 5.67 ▼               • isoprot 10mg  ...... 7.49                 • comparison         normalized:             • control  ...... 0.219               • atenolol 10mg  ...... 0.230               • isoprot 1mg  ...... 0.280               • isoprot 10mg  ...... 0.332                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 ventricle (both) weight [mg]     control and  atenolol, isoproterenol 2wks       weight:             • control  ...... 78.3 ▼               • atenolol 10mg  ...... 77.6 ▼               • isoprot 1mg  ...... 81.9 ▼               • isoprot 10mg  ...... 102                 • comparison         normalized:             • control  ...... 3.98               • atenolol 10mg  ...... 3.83               • isoprot 1mg  ...... 4.04               • isoprot 10mg  ...... 4.54                 • comparison   23 strains   age 7-13wks   Inbred Maurer1 atria weight to ventricle weight ratio [ratio]     control and  atenolol, isoproterenol 2wks       • control  ...... 18.2         • atenolol 10mg  ...... 16.7         • isoprot 1mg  ...... 14.5         • isoprot 10mg  ...... 13.7           • comparison   23 strains   age 7-13wks   Inbred Reed1 heart weight         • weight [g]  ...... 0.131         • as percent of body weight [%]  ...... 0.496         28 strains   age 29-67wks   Inbred   eye — morphology         metric   Chang1 eye diameter   [mm] ...... 3.50 (N=4)   17 strains   age >7wks   Inbred   kidney — morphology — weight         scales   Harrill2 kidney (left) weight [g]     control and  DB289       • control  ...... 0.164 ▲         • DB289  ...... 0.105 (N=4)           • comparison   34 strains   age 6-8wks   Inbred Harrill2 kidney (right) weight [g]     control and  DB289       • control  ...... 0.136         • DB289  ...... 0.107 (N=4)           • comparison   34 strains   age 6-8wks   Inbred Harrill2 kidney (both) weight [g]     control and  DB289       • control  ...... 0.300         • DB289  ...... 0.212 (N=4)           • comparison   34 strains   age 6-8wks   Inbred Harrill2 total kidney weight as percent of body weight [%]     control and  DB289       • control  ...... 1.82 ▲         • DB289  ...... 1.46 (N=4)         • difference  ...... 0.802 ▼         34 strains   age 6-8wks   Inbred Reed1 kidney weight         • weight [g]  ...... 0.460         • as percent of body weight [%]  ...... 1.74         28 strains   age 29-67wks   Inbred   liver — weight         scales   Harrill2 liver weight at sacrifice [g]     control and  DB289       • control  ...... 0.690         • DB289  ...... 0.478 (N=4)           • comparison   34 strains   age 6-8wks   Inbred Harrill2 liver weight as percent of body weight [%]     control and  DB289       • control  ...... 4.18         • DB289  ...... 3.32 (N=4)         • difference  ...... 0.794 ▼         34 strains   age 6-8wks   Inbred Paigen1 liver weight at sacrifice   [g] ...... 2.49 ▲   2.09     high-fat diet   8wks 43 strains   age 15-19wks   Inbred Threadgill1 liver weight [g]     control and  acetaminophen       • control  ...... 1.06         24h post-Rx mg/kg:             • 100  ......             • 200  ......             • 300  ...... 1.26 (N=3)                 • comparison   37 strains   age 8-17wks   Inbred

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