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Phenotype data: respiratory all
Phenotype data >
respiratory
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airway resistance
breathing pattern
immune function
lung compliance
lung volume
mechanics
pulmonary gas exchange
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respiratory — airway resistance         ventilator  
Berndt1
resistance [cm/mL/s]  
      • untreated 
36 strains   age 9-12wks
  Inbred
Berndt1
resistance [cm/mL/s]     baseline and  methacholine
      • baseline    MCh challenge (mg/mL): • 1   • 3   • 10   • 30    • comparison  
36 strains   age 9-12wks
  Inbred
Berndt1
resistance (percent of baseline) [%]   methacholine
      MCh challenge (mg/mL): • 1   • 3   • 10   • 30    • comparison  
36 strains   age 9-12wks
  Inbred
Berndt2
airway resistance (H20 pressure) [cm/mL/s]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 1    • 3    • 10    • 30    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
Schulz1
resistance  
      • system resistance [cm/mL/s] 
      • system resistance adjusted to lung capacity [cm⋅s] 
        • comparison  
7 strains   age 12-14wks
  Inbred
 
respiratory — breathing pattern — airflow rate         plethysmography  
Berndt2
inspiratory flow rate [mL/kg/s]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
Berndt2
expiratory flow rate [mL/kg/s]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
Berndt2
respiratory flow rate [mL/kg/s]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
 
respiratory — breathing pattern — cycle         plethysmography  
Berndt2
inspiratory phase [s]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
Berndt2
expiratory phase [s]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
Berndt2
respiratory cycle [s]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
Berndt2
duty cycle [ratio]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
 
respiratory — breathing pattern — efficiency         plethysmography  
Berndt2
minute ventilation [mL/min]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
Berndt2
breath frequency [n/min]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
 
respiratory — breathing pattern — enhanced pause         plethysmography  
Berndt2
enhanced pause     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
 
respiratory — immune function — response to antigen         cytospin centrifuge  
Schwartz2
alveolar eosinophils [%]     control and  ovalbumin i.p.
        pre-test:   • control    • OVA-sensitized    • comparison  
        24h post:   • control    • OVA-sensitized    • comparison  
        48h post:   • control    • OVA-sensitized    • comparison  
        72h post:   • control    • OVA-sensitized    • comparison  
        time curves:   control    OVA-sensitized 
8 strains   age 6-8wks
  Inbred
Schwartz2
alveolar lymphocytes [%]     control and  ovalbumin i.p.
        pre-test:   • control    • OVA-sensitized    • comparison  
        24h post:   • control    • OVA-sensitized    • comparison  
        48h post:   • control    • OVA-sensitized    • comparison  
        72h post:   • control    • OVA-sensitized    • comparison  
        time curves:   control    OVA-sensitized 
8 strains   age 6-8wks
  Inbred
Schwartz2
alveolar neutrophils [%]     control and  ovalbumin i.p.
        pre-test:   • control    • OVA-sensitized    • comparison  
        24h post:   • control    • OVA-sensitized    • comparison  
        48h post:   • control    • OVA-sensitized    • comparison  
        72h post:   • control    • OVA-sensitized    • comparison  
        time curves:   control    OVA-sensitized 
8 strains   age 6-8wks
  Inbred
 
respiratory — lung compliance         ventilator  
Berndt2
lung tissue dynamic elastance (H20 pressure) [cm/mL]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 1    • 3    • 10    • 30    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
Schulz1
compliance [µL/cm]  
      • static (system)  • static (lung)  • dynamic    • comparison  
7 strains   age 12-14wks
  Inbred
Schulz1
compliance adjusted to lung capacity [1/cm]  
      • static  • dynamic    • comparison  
7 strains   age 12-14wks
  Inbred
 
respiratory — lung volume         plethysmography  
Berndt2
tidal volume [mL]     baseline and  methacholine
        • saline    MCh [mg/mL]:   • 5    • 10    • 20    • comparison  
        • MCh response index 
29 strains   age 9-12wks
  Inbred
 
respiratory — lung volume         ventilator  
Schulz1
volume [µL]  
      • alveolar 
7 strains   age 12-14wks
  Inbred
 
respiratory — mechanics         ventilator  
Schulz1
capacity [µL]  
      • inspiratory  • residual  • total  • vital    • comparison  
7 strains   age 12-14wks
  Inbred
Schulz1
capacity (adjusted)  
      • total adjusted to body weight [µL/g] 
      • vital adjusted to body weight [µL/g] 
      • residual adjusted to body weight [µL/g] 
      • residual adjusted to lung capacity [µL/µL] 
        • comparison  
7 strains   age 12-14wks
  Inbred
Schulz1
dead space  
      • Fowler adjusted to lung capacity [µL/µL] 
      • Fowler adjusted to body weight [µL/g] 
      • Fowler dead space volume 
        • comparison  
7 strains   age 12-14wks
  Inbred
 
respiratory — pulmonary gas exchange         ventilator  
Schulz1
gas mixing and diffusing capacity  
      • gas mixing [mm/mL] 
      • diffusing capacity [µmol/min/hPa] 
      • diffusing capacity adjusted to alveolar volume [µmol/min/hPa/mL] 
        • comparison  
7 strains   age 12-14wks
  Inbred


123 measurements listed.

 


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