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Phenotype data: respiratory airway resistance
Phenotype data > C57BR/cdJ strain >
respiratory
Options:
airway resistance
breathing pattern
lung compliance
lung volume
all
Focus: airway resistance
Measurements:


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C57BR/cdJ
averages
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respiratory — airway resistance         ventilator  
Berndt1
resistance [cm/mL/s]  
      • untreated  ...... 0.343   0.333  
     
36 strains   age 9-12wks
  Inbred
Berndt1
resistance [cm/mL/s]     baseline and  methacholine
      • baseline  ...... 0.356   0.379  
      MCh challenge (mg/mL):
            • 1  ...... 0.531   0.457  
            • 3  ...... 0.679   0.743  
            • 10  ...... 1.22   1.27  
            • 30  ...... 1.81 (N=4)   1.54  
              • comparison  
36 strains   age 9-12wks
  Inbred
Berndt1
resistance (percent of baseline) [%]   methacholine
      MCh challenge (mg/mL):
            • 1  ...... 48.5 ▲▲   20.4  
            • 3  ...... 93.7   94.6  
            • 10  ...... 235   235  
            • 30  ...... 452 (N=4)   315  
              • comparison  
36 strains   age 9-12wks
  Inbred
Berndt2
airway resistance (H20 pressure) [cm/mL/s]     baseline and  methacholine
      • saline  ...... 0.356   0.379  
      MCh [mg/mL]:
            • 1  ...... 0.531   0.457  
            • 3  ...... 0.679   0.743  
            • 10  ...... 1.22   1.27  
            • 30  ...... 1.81 (N=4)   1.54  
              • comparison  
      • MCh response index  ...... 0.347   0.410  
     
29 strains   age 9-12wks
  Inbred


 


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