Home       About             Help       Phenotype data > CAST/EiJ strain > neurosensory Options: nociception sensory gating all Focus: all Measurements: About these CAST/EiJ averages (♀ ♂) Exit CAST/EiJ mode neurosensory — nociception — chemical         nociception assay   Koide2 capsaicin solution consumption, percent of baseline [%]         concentration (µM):             • 0.5  ...... 94.3   99.8               • 1  ...... 95.9   94.4               • 4  ...... 82.4 ▲   81.5               • 7  ...... 81.4 ▲   72.2 ▲               • 10  ...... 64.0 ▲   62.6 ▲               • 15  ...... 47.7   44.2                 • comparison   14 strains   age 8-12wks   wild-derived Mishima   neurosensory — nociception — mechanical         nociception assay   Chesler2 latency of nociceptive response to pressure on the tail, 60 s test   [s] ...... 10.5 ▼   27.9 (N=2)   62 strains   age various   CC diallel Chesler3 latency of nociceptive response to pressure on the tail, 60 s test   [s] ...... 10.5 ▼   27.9 (N=2)   age various   CC pre   neurosensory — nociception — thermal         nociception assay   Chesler2 latency of nociceptive response to hot plate (54°C), 30 s test   [s] ...... 3.59 ▼   6.94 (N=2) ▲   62 strains   age various   CC diallel Chesler3 latency of nociceptive response to hot plate (54°C), 30 s test   [s] ...... 3.59   6.94 (N=2)   age various   CC pre Koide1 sensitivity to thermal-induced pain         • tail flick  ...... 3.94         • hot plate (lick)  ...... 18.7         • hot plate (jump)  ...... 62.6 ▼         11 strains   age 8-13wks   wild-derived Mishima   neurosensory — sensory gating         acoustic startle test   Willott1 acoustic startle response (ASR)         sound pressure level:             • 70dB  ...... 58.3   63.0               • 80dB  ...... 71.1 ▼   87.7               • 90dB  ...... 172   246               • 100dB  ...... 233   298                 • comparison   40 strains   age 5-6wks   Inbred Willott1 acoustic startle response (ASR)         • mean latency evoked by 100dB  ...... 30.9   32.7 ▲         • habituation ratio  ...... 1.63 ▲▲   1.02         40 strains   age 5-6wks   Inbred Willott1 mean prepulse inhibition (PPI), 70dB [ratio]         • 4kHz  ...... 0.841   0.910         • 12kHz  ...... 0.755   0.705         • 20kHz  ...... 0.603   0.648         • all tones  ...... 2.20   2.26           • comparison   40 strains   age 5-6wks   Inbred

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