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Phenotype data
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NZB/BlNJ strain
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liver
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lipid homeostasis
mineral homeostasis
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Phenotype data: liver all
Measurements:
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NZB/BlNJ
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liver — lipid homeostasis
lipid profile
Paigen1
hepatic cholesterol concentration [mg]
high-fat diet
8wks
• free
......
6.90
▲
6.02
• esterified
......
48.5
20.1
• total
......
60.2
▲
41.0
• free to esterified ratio
......
0.143
0.304
43
strains
age
15-19wks
Inbred
Schonfeld1
hepatic triglycerides (5h fast)
[mg/g] ......
63.0
91.1
10
strains
age
9-13wks
Inbred
liver — mineral homeostasis
mass spectrometry
Vulpe1
liver mineral [µg/g]
• copper
......
16.9
▲▲
20.9
▲
• iron
......
243
▼
227
• zinc
......
94.5
▲▲
82.2
• comparison
18
strains
age
8wks
Inbred
liver — pathology
histopathology
Paigen1
liver pathology (0-4) [score]
high-fat diet
8wks
• images
......
• microvacuoles
......
3.00
(N=3)
2.33
(N=3)
• macrovacuoles
......
0
(N=3)
0
(N=3)
• inflammation
......
2.33
(N=3)
▲▲
3.00
(N=3)
▲▲
43
strains
age
15-19wks
Inbred
liver — weight
scales
Paigen1
liver weight at sacrifice
[g] ......
2.00
2.85
▲
high-fat diet
8wks
43
strains
age
15-19wks
Inbred
Schonfeld1
liver weight
[g] ......
1.00
1.03
10
strains
age
9-13wks
Inbred
Schonfeld1
liver weight as a percent of body weight
[%] ......
4.49
3.85
▼
10
strains
age
9-13wks
Inbred
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