Home       About             Help       Phenotype data > DBA/2J strain > kidney Options: function morphology all Focus: all Measurements: About these DBA/2J averages (♀ ♂) Exit DBA/2J mode kidney — function — flow         gauge   Gupta1 urethral hydrostatic pressure (at which dye is observed flowing)   [cm] ...... 60.0   60.0 (N=2)   8 strains   age postnatal d1   Inbred Gupta1 vesico-ureteric reflux (VUR) index   [score] ...... 2.60 ▲   3.00 (N=2) ▲   8 strains   age postnatal d1   Inbred   kidney — function — urinalysis         ELISA   Harrill2 urine kidney injury molecule 1 (KIM-1) [pg]     control and  DB289       • control  ...... 291         • DB289  ...... 1273         • difference  ...... 4.38         34 strains   age 6-8wks   Inbred   kidney — function — urinalysis         spectrophotometry   Rusyn5 urine alcohol concentration (UAC), daily average [mg/dL]   high-fat diet , ethanol       • high-fat only  ...... 20.3 (N=3)         • high-fat and ethanol  ...... 143 (N=3)           • comparison   14 strains   age 8-14wks   Inbred Rusyn5 urine alcohol concentration (UAC), daily peak [mg/dL]   high-fat diet , ethanol       • high-fat only  ...... 68.5 (N=3)         • high-fat and ethanol  ...... 545 (N=3)           • comparison   14 strains   age 8-14wks   Inbred   kidney — function — urinalysis         urinalysis   DiPetrillo1 microalbumin (urine MA)   [mg/dL] ...... 12.4 ▲▲   34 strains   age 10wks   Inbred DiPetrillo1 creatinine (urine CREA)   [mg/dL] ...... 87.2   34 strains   age 10wks   Inbred DiPetrillo1 albumin-creatinine ratio (urine ACR)   [mg/g] ...... 143 ▲▲   34 strains   age 10wks   Inbred Harrill2 urine volume [mL]     control and  DB289       • control  ...... 0.960         • DB289  ...... 1.72         • difference  ...... 1.79 ▲         34 strains   age 6-8wks   Inbred Harrill2 creatinine (urine CREA) [mg/mL]     control and  DB289       • control  ...... 0.142         • DB289  ...... 0.132         • difference  ...... 0.930         34 strains   age 6-8wks   Inbred Korstanje1 microalbumin (urine MA) [mg/dL]         • 12mo  ...... 4.95   0.734         • 18mo  ...... 1.54   2.17         • 24mo  ...... 0.973   5.25           • age comparison   30 strains   ages shown   Inbred Korstanje1 creatinine (urine CREA) [mg/dL]         • 12mo  ...... 73.8   81.7         • 18mo  ...... 73.9   79.5         • 24mo  ...... 90.4   73.5           • age comparison   30 strains   ages shown   Inbred Korstanje1 albumin-creatinine ratio (urine ACR) [mg/g]         • 12mo  ...... 98.2   9.60         • 18mo  ...... 23.0   23.5         • 24mo  ...... 12.5   71.3           • age comparison   30 strains   ages shown   Inbred   kidney — morphology — area         metric   Gupta1 kidney planar surface area [mm2]         • left  ...... 5.40   5.18 (N=2)         • right  ...... 4.56   5.12 (N=2)           • comparison   8 strains   age postnatal d1   Inbred Gupta1 normalized kidney planar surface area [mm2/g]         • left  ...... 4.41 ▲   3.88 (N=2)         • right  ...... 3.71   3.84 (N=2)           • comparison   7 strains   age postnatal d1   Inbred   kidney — morphology — weight         scales   Deschepper1 kidney weight [mg]         weight:             • both  ...... 258   349               • left  ...... 131   175               • right  ...... 127   174         normalized:             • both  ...... 13.8   14.9               • left  ...... 7.01   7.45               • right  ...... 6.76   7.44               13 strains   age 10wks   Inbred Gupta1 kidney weight [g]         • left  ...... 0.00642   0.00715 (N=2)         • right  ...... 0.00602 ▼   0.00720 (N=2)         • both  ...... 0.0124 ▼   0.0143 (N=2)           • comparison   7 strains   age postnatal d1   Inbred Gupta1 percent kidney weight to body weight [%]         • left  ...... 0.522 ▲   0.536 (N=2) ▲         • right  ...... 0.491   0.538 (N=2)         • both  ...... 1.01   1.07 (N=2) ▲           • comparison   7 strains   age postnatal d1   Inbred Harrill2 kidney (left) weight [g]     control and  DB289       • control  ...... 0.132         • DB289  ...... 0.116           • comparison   34 strains   age 6-8wks   Inbred Harrill2 kidney (right) weight [g]     control and  DB289       • control  ...... 0.126         • DB289  ...... 0.116           • comparison   34 strains   age 6-8wks   Inbred Harrill2 kidney (both) weight [g]     control and  DB289       • control  ...... 0.254         • DB289  ...... 0.236           • comparison   34 strains   age 6-8wks   Inbred Harrill2 total kidney weight as percent of body weight [%]     control and  DB289       • control  ...... 1.38         • DB289  ...... 1.39         • difference  ...... 1.01         34 strains   age 6-8wks   Inbred Jaxpheno2 kidney (left) weight [g]         • age 8wks  ...... 0.102 ▼   0.167         • age 16wks  ...... 0.169 ▲   0.253           • age comparison   11 strains   ages shown   Inbred Jaxpheno2 kidney (right) weight [g]         • age 8wks  ...... 0.110 ▼   0.164         • age 16wks  ...... 0.170 ▲   0.256           • age comparison   11 strains   ages shown   Inbred Jaxpheno2 kidney (left) weight, as percent of body weight [%]         • age 8wks  ...... 0.565   0.731         • age 16wks  ...... 0.628   0.870           • age comparison   11 strains   ages shown   Inbred Jaxpheno2 kidney (right) weight, as percent of body weight [%]         • age 8wks  ...... 0.603   0.718         • age 16wks  ...... 0.630   0.880           • age comparison   11 strains   ages shown   Inbred Reed1 kidney weight         • weight [g]  ...... 0.665         • as percent of body weight [%]  ...... 2.36 ▲         28 strains   age 29-67wks   Inbred   kidney — xenobiotics — drug and metabolite concentration         HPLC   Harrill2 kidney metabolite (DB75) concentration [µM]     control and  DB289       • control  ...... 0 (N=3)         • DB289  ...... 842           • comparison   34 strains   age 6-8wks   Inbred

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