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immune system
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cell counts – peripheral blood
cell counts – spleen
cell counts – thymus
histocompatibility
immunoglobulins
morphology – thymus
proteins
response to infections
all
See also:
gene expression, macrophage
respiratory
spleen
Other related resources of interest
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Phenotype data: immune system all
Measurements:
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immune system — cell counts — peripheral blood — B cells
flow cytometry
Petkova1
B cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Donahue5
B cells (percent of viable WBC)
[%]
22
strains
age
7wks
B6.A consomic
Donahue6
B cells (percent of viable WBC)
[%]
28
strains
age
7wks
B6.PWD consomic
immune system — cell counts — peripheral blood — NK cells
flow cytometry
Petkova1
NK cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Donahue5
natural killer (NK) cells [%]
• total
• mature
22
strains
age
7wks
B6.A consomic
Donahue6
natural killer (NK) cells [%]
• total
• mature
28
strains
age
7wks
B6.PWD consomic
immune system — cell counts — peripheral blood — T cells
flow cytometry
Petkova1
CD4 T cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Petkova1
CD4 T cells - naive cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Petkova1
CD4 T cells - central memory cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Petkova1
CD4 T cells - effector memory cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Petkova1
CD4 T cells - effector cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Petkova1
CD8 T cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Petkova1
CD8 T cells - naive cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Petkova1
CD8 T cells - central memory cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Petkova1
CD8 T cells - effector memory cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Petkova1
CD8 T cells - effector cells [%]
• 6mo
• 12mo
• 18mo
• 24mo
• age comparison
32
strains
ages shown
Inbred
Donahue5
T cells [%]
• total
• CD4 T cells
• CD8 T cells
22
strains
age
7wks
B6.A consomic
Donahue6
T cells [%]
• total
• CD4 T cells
• CD8 T cells
28
strains
age
7wks
B6.PWD consomic
immune system — cell counts — spleen
flow cytometry
Benoist1
CD4 T cells [%]
• CD25hi
• Foxp3+
• comparison
31
strains
age
5-6wks
Inbred
Jaxpheno6
CD4 T cells [%]
• 8wks
• 16wks
• age comparison
11
strains
ages shown
Inbred
Jaxpheno6
CD8 T cells [%]
• 8wks
• 16wks
• age comparison
11
strains
ages shown
Inbred
Jaxpheno6
NK T cells [%]
• 8wks
• 16wks
• age comparison
11
strains
ages shown
Inbred
Jaxpheno6
NK cells [%]
• 8wks
• 16wks
• age comparison
11
strains
ages shown
Inbred
Jaxpheno6
B cells [%]
• 8wks
• 16wks
• age comparison
11
strains
ages shown
Inbred
Jaxpheno6
granulocytes [%]
• 8wks
• 16wks
• age comparison
11
strains
ages shown
Inbred
Jaxpheno6
monocytes [%]
• 8wks
• 16wks
• age comparison
11
strains
ages shown
Inbred
Williams1
CD4 T cells - regulatory (Treg) [%]
• percent of lymphocytes
• percent of CD4 T cells
• comparison
5
strains
age
8wks
Inbred
Williams1
CD4 T cells - memory effector [%]
• percent of lymphocytes
• percent of CD4 T cells
• comparison
5
strains
age
8wks
Inbred
Williams1
CD4 T cells - naive [%]
• percent of lymphocytes
• percent of CD4 T cells
• comparison
5
strains
age
8wks
Inbred
Williams1
profile
by total lymphocytes
by total CD4 Tcells
5
strains
age
8wks
Inbred
immune system — cell counts — thymus
flow cytometry
Benoist1
CD4 T cells [%]
• CD25hi
• Foxp3+
• comparison
33
strains
age
5-6wks
Inbred
immune system — histocompatibility — MHC haplotype
Jax2
major histocompatibility complex (MHC) H2 haplotype
[designation]
57
strains
Inbred
immune system — immunoglobulins
ELISA
Donahue7
concentration (plasma) [µg/mL]
• IgA
• IgG
• IgM
• comparison
22
strains
age
9wks
B6.A consomic
Donahue8
concentration (plasma) [µg/mL]
• IgA
• IgG
• IgM
• comparison
22
strains
age
9wks
B6.PWD consomic
immune system — immunoglobulins
flow cytometry
Eumorphia7
concentration (serum) [µg/mL]
• IgA
• IgG1
• IgG2a
• IgG2b
• IgG3
• IgM
• comparison
6
strains
age
9-12wks
Inbred
immune system — morphology — thymus
scales
Deschepper1
thymus weight [mg]
• weight
• normalized
13
strains
age
10wks
Inbred
immune system — proteins — misc
PCR
Gros1
complement component 5 (C5) allele (0=deficient, 1=sufficient)
[designation]
36
strains
age
8-12wks
Inbred
immune system — response to bacterial infection — anthrax
in vitro assay
Dietrich1
macrophage susceptibility to Bacillus anthracis
lethal toxin (0=susceptible; 1=resistant)
[designation]
Bacillus anthracis lethal toxin
50
strains
age
6-8wks*
Inbred
immune system — response to fungal infection — candidiasis
colony-forming units
Gros1
kidney fungal load 48h post-infection,
colony-forming units (log
10
CFU per kidney)
[n]
Candida albicans
23
strains
age
8-12wks
Inbred
Gros1
susceptibility to C. albicans based on fungal load
(0=susceptible; 1=resistant)
[designation]
Candida albicans
23
strains
age
8-12wks
Inbred
immune system — response to parasitic infection — malaria
flow cytometry
Bopp1
parasite distribution in selected organs [%]
Plasmodium berghei
• brain
• spleen
• lungs
• liver
• comparison
26
strains
age
8-12wks
Inbred
immune system — response to parasitic infection — malaria
observation
Bopp1
response to infection
Plasmodium berghei
• survival
• body temperature
• parasite load
31
strains
age
8-12wks
Inbred
immune system — response to viral infection
in vitro assay
Ferris1
viral replication log titer, day 4 post-infection (lung)
[n]
influenza A (H1N1) virus
age
8-16wks
CC pre
immune system — response to viral infection
observation
Boon1
survival [d]
influenza A (H5N1) virus
dosage group:
• low
• medium
• high
• comparison
18
strains
age
6-9wks
Inbred
Boon1
susceptibility to viral infection [designation]
influenza A (H5N1) virus
dosage group:
• low
• medium
• high
• comparison
18
strains
age
6-9wks
Inbred
Schughart1
susceptibility to viral infection
(0=susceptible; 1=resistant)
[designation]
influenza A (H1N1) virus
9
strains
age
10-12wks
Inbred
Ferris1
clinical score, day 4 post-infection (score 0-4)
[score]
influenza A (H1N1) virus
age
8-16wks
CC pre
Ferris1
susceptibility to viral infection index (0=susceptible; 1= resistant)
[score]
influenza A (H1N1) virus
age
8-16wks
CC pre
immune system — response to viral infection — other-cat3
histopathology
Ferris1
virus-induced airway inflammation, day 4 post-infection (score 0-3)
[score]
influenza A (H1N1) virus
age
8-16wks
CC pre
Ferris1
virus-induced airway neutrophils, day 4 post-infection (score 0-3)
[score]
influenza A (H1N1) virus
age
8-16wks
CC pre
Ferris1
virus-induced airway damage, day 4 post-infection (score 0-3)
[score]
influenza A (H1N1) virus
age
8-16wks
CC pre
Ferris1
virus-induced vascular inflammation (lung), day 4 post-infection (score 0-3)
[score]
influenza A (H1N1) virus
age
8-16wks
CC pre
Ferris1
virus-induced alveoar inflammation, day 4 post-infection (score 0-3)
[score]
influenza A (H1N1) virus
age
8-16wks
CC pre
Ferris1
virus-induced alveolar damage, day 4 post-infection (score 0-3)
[score]
influenza A (H1N1) virus
age
8-16wks
CC pre
Ferris1
virus-induced pulmonary edema, day 4 post-infection (score 0-3)
[score]
influenza A (H1N1) virus
age
8-16wks
CC pre
127 measurements listed.
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