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Phenotype data: immune system cell counts – peripheral blood
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immune system
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Focus: cell counts – peripheral blood
Measurements:


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C57BL/6J
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immune system — cell counts — peripheral blood — B cells         flow cytometry  
Petkova1
B cells [%]  
      • 6mo  ...... 68.1   82.0  
      • 12mo  ...... 74.0 ▲▲   77.2  
      • 18mo  ...... 76.5 ▲▲   74.7  
      • 24mo  ...... 58.0   50.0  
        • age comparison  
32 strains   ages shown
  Inbred
Donahue5
B cells (percent of viable WBC)   [%] ...... 57.6   60.2  
22 strains   age 7wks
  B6.A consomic
Donahue6
B cells (percent of viable WBC)   [%] ...... 57.6   60.2  
28 strains   age 7wks
  B6.PWD consomic
 
immune system — cell counts — peripheral blood — NK cells         flow cytometry  
Petkova1
NK cells [%]  
      • 6mo  ...... 3.75   4.03  
      • 12mo  ...... 9.21 ▲▲   4.31  
      • 18mo  ...... 6.02   5.30  
      • 24mo  ...... 3.50   7.21  
        • age comparison  
32 strains   ages shown
  Inbred
Donahue5
natural killer (NK) cells [%]  
      • total  ...... 5.55   4.96  
      • mature  ...... 4.79   4.06  
     
22 strains   age 7wks
  B6.A consomic
Donahue6
natural killer (NK) cells [%]  
      • total  ...... 5.55   4.96  
      • mature  ...... 4.79   4.06  
     
28 strains   age 7wks
  B6.PWD consomic
 
immune system — cell counts — peripheral blood — T cells         flow cytometry  
Petkova1
CD4 T cells [%]  
      • 6mo  ...... 7.48   4.19  
      • 12mo  ...... 3.96   4.56  
      • 18mo  ...... 6.13   5.14  
      • 24mo  ...... 7.90   7.45  
        • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD4 T cells - naive cells [%]  
      • 6mo  ...... 44.1   57.6  
      • 12mo  ...... 6.13   31.7  
      • 18mo  ...... 31.0   37.6  
      • 24mo  ...... 6.75   22.1  
        • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD4 T cells - central memory cells [%]  
      • 6mo  ...... 7.81   5.16  
      • 12mo  ...... 6.72   6.76  
      • 18mo  ...... 8.95   7.44  
      • 24mo  ...... 8.81   10.4  
        • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD4 T cells - effector memory cells [%]  
      • 6mo  ...... 16.4   6.56  
      • 12mo  ...... 37.9   16.3  
      • 18mo  ...... 30.7   27.7  
      • 24mo  ...... 64.9   36.1  
        • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD4 T cells - effector cells [%]  
      • 6mo  ...... 31.7   30.7  
      • 12mo  ...... 49.2   45.1  
      • 18mo  ...... 29.3   27.3  
      • 24mo  ...... 19.5   31.3  
        • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD8 T cells [%]  
      • 6mo  ...... 16.0   7.42  
      • 12mo  ...... 6.29   12.3  
      • 18mo  ...... 7.38   8.51  
      • 24mo  ...... 11.8   17.6  
        • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD8 T cells - naive cells [%]  
      • 6mo  ...... 64.9   59.1  
      • 12mo  ...... 19.3   45.0  
      • 18mo  ...... 28.8   38.3  
      • 24mo  ...... 3.20   18.4  
        • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD8 T cells - central memory cells [%]  
      • 6mo  ...... 15.0   19.6  
      • 12mo  ...... 18.2   30.2  
      • 18mo  ...... 41.2   30.5  
      • 24mo  ...... 32.2   43.1  
        • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD8 T cells - effector memory cells [%]  
      • 6mo  ...... 4.89   3.90  
      • 12mo  ...... 33.4   11.1  
      • 18mo  ...... 21.4   20.8  
      • 24mo  ...... 51.3   22.3  
        • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD8 T cells - effector cells [%]  
      • 6mo  ...... 15.3   17.5  
      • 12mo  ...... 29.1   13.7  
      • 18mo  ...... 8.47   10.5  
      • 24mo  ...... 13.4   16.3  
        • age comparison  
32 strains   ages shown
  Inbred
Donahue5
T cells [%]  
      • total  ...... 17.8   16.5  
      • CD4 T cells  ...... 7.94   7.91  
      • CD8 T cells  ...... 8.81   7.64  
     
22 strains   age 7wks
  B6.A consomic
Donahue6
T cells [%]  
      • total  ...... 17.8   16.5  
      • CD4 T cells  ...... 7.94   7.91  
      • CD8 T cells  ...... 8.81   7.64  
     
28 strains   age 7wks
  B6.PWD consomic


 


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