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endocrine
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hormones
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Phenotype data: endocrine hormones
Measurements:
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endocrine — hormones
radioimmunoassay
Donahue1
osteocalcin (serum OC)
[ng/mL]
30
strains
age
15-16wks
Inbred
Pletcher1
serum corticosterone [µg/dL]
• untransformed
• log-transformed
29
strains
age
7-10wks*
Inbred
endocrine — hormones — IGF-1
radioimmunoassay
Donahue1
insulin-like growth factor 1 (adjusted serum IGF-1)
[ng/mL]
30
strains
age
15-16wks
Inbred
Yuan1
insulin-like growth factor 1 (serum IGF-1) [ng/mL]
• 6mo
• 12mo
• 18mo
• age comparison
33
strains
ages shown
Inbred
endocrine — hormones — insulin
ELISA
Naggert1
insulin
[ng/mL]
high-fat diet
18wks
43
strains
age
25-27wks
Inbred
endocrine — hormones — insulin
radioimmunoassay
Schonfeld1
insulin level (plasma), 30 min post injection in glucose tolerance test
(10% glucose i.p., 5h fast)
[ng/mL]
10
strains
age
9-13wks
Inbred
Cheverud1
insulin (serum) [ng/mL]
control and
high-fat diet
17wks
• control diet
• high-fat diet
• comparison
19
strains
age
20-30wks
LGXSM
endocrine — hormones — leptin
ELISA
Naggert1
leptin
[pg/mL]
high-fat diet
18wks
43
strains
age
25-27wks
Inbred
endocrine — hormones — leptin
radioimmunoassay
Cheverud1
leptin (serum) [pg/mL]
control and
high-fat diet
17wks
• control diet
• high-fat diet
• comparison
19
strains
age
20-30wks
LGXSM
endocrine — hormones — thyroxine
metabolic panel
CGDpheno1
thyroxine (plasma T4)
[µg/dL]
72
strains
age
12wks
Inbred
Donahue1
thyroxine (serum T4)
[µg/dL]
30
strains
age
15-16wks
Inbred
Jaxpheno3
thyroxine (plasma T4) [µg/dL]
• age 8wks
• age 16wks
• age comparison
11
strains
ages shown
Inbred
Shockley1
thyroxine (T4) [µg/dL]
control and
high-fat diet
4wks
• control diet
• high-fat diet
• difference
• comparison
10
strains
age
10-13wks
Inbred
Yuan3
thyroxine (serum T4) [µg/dL]
• 6mo
• 12mo
• 18mo
• age comparison
31
strains
ages shown
Inbred
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