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Phenotype data
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PWK/PhJ strain
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bone
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mineral density and content – femur
mineral density and content – skull
mineral density and content – spine
mineral density and content – whole body
mineral density and content – all
morphology – area
morphology – craniofacial
morphology – femur
strength – femur
all
Focus:
all
Phenotype data: bone all
Measurements:
About these
PWK/PhJ
averages
(
♀
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)
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PWK/PhJ
mode
bone — mineral density and content — femur
DXA
Donahue2
volumetric bone mineral density (vBMD), whole left femur
[g/cm
3
] ......
0.641
0.603
10
strains
age
16wks
Inbred
Donahue2
cortical shell volumetric bone mineral density (vBMD), whole left femur
[g/cm
3
] ......
1.07
▼
1.06
▼
10
strains
age
16wks
Inbred
Donahue2
cross sectional volumetric bone mineral density (vBMD), right femur mid-diaphysis
[g/cm
3
] ......
0.714
0.711
10
strains
age
16wks
Inbred
Donahue2
cross sectional bone mineral content (BMC), right femur mid-diaphysis
[g] ......
1.00
▼
1.04
▼
10
strains
age
16wks
Inbred
bone — mineral density and content — skull
DXA
Donahue1
skull bone mineral density
[g/cm
2
] ......
0.106
0.103
30
strains
age
15-16wks
Inbred
Churchill1
skull bone mineral density
[g/cm
2
] ......
0.114
▼
0.112
▼
63
strains
age
7-8wks
8-way diallel
bone — mineral density and content — spine
DXA
Donahue1
spine (L2-L5) bone mineral density
[g/cm
2
] ......
0.0759
0.0606
30
strains
age
15-16wks
Inbred
Churchill1
vetebral spine bone mineral density
[g/cm
2
] ......
0.0754
▼
0.0593
▼▼
63
strains
age
7-8wks
8-way diallel
bone — mineral density and content — whole body without head
DXA
CGDpheno1
whole body bone mineral density
[g/cm
2
] ......
72
strains
age
13wks
Inbred
Donahue1
bone mineral density and content
• BMD
......
0.0429
0.0412
▼
• BMC
......
0.337
0.304
▼
30
strains
age
15-16wks
Inbred
Naggert1
bone mineral density and content
high-fat diet
8wks
• BMD
......
0.0438
▼
• BMC
......
0.338
▼
43
strains
age
15-17wks
Inbred
Tordoff3
bone mineral density and content
• BMD
......
0.0465
▼
0.0452
▼
• BMC
......
0.319
▼
0.315
▼
40
strains
age
14-18wks
Inbred
Churchill1
whole body bone mineral density (BMD)
[g/cm
2
] ......
0.0456
▼▼
0.0419
▼▼
63
strains
age
7-8wks
8-way diallel
CGDpheno3
bone mineral density and content
• BMD
......
0.0540
▼
0.0520
• BMC
......
0.208
▼
0.200
▼
42
strains
age
16wks
CC diallel
bone — morphology — area
DXA
CGDpheno3
whole body bone area, head excluded
[cm
2
] ......
4.70
4.61
42
strains
age
16wks
CC diallel
bone — morphology — craniofacial
DXA
Donahue1
skull [mm]
• length
......
21.8
21.9
• height
......
9.34
9.54
• width
......
9.33
9.53
29
strains
age
15-16wks
Inbred
Donahue1
facial [mm]
• nasal length
......
15.0
15.2
• distance between eyes
......
5.71
6.01
29
strains
age
15-16wks
Inbred
Donahue1
mandibular length [mm]
• upper jaw
......
16.2
16.2
• lower jaw
......
9.83
10.2
29
strains
age
15-16wks
Inbred
bone — morphology — femur
DXA
Donahue2
femur cortical thickness [mm]
• right (pQCT)
......
0.187
0.191
▼
• right (µCT)
......
0.209
0.208
• left (pQCT)
......
0.194
0.186
▼
10
strains
age
16wks
Inbred
Donahue2
femoral cross-sectional geometry (pQCT) [mm]
• periosteal (outer)
......
4.00
▼▼
3.94
▼▼
• endosteal (inner)
......
2.79
▼
2.77
▼
• cross sectional area
......
1.41
▼▼
1.46
▼▼
10
strains
age
16wks
Inbred
bone — morphology — femur
metric
Donahue2
femoral dimensions [mm]
• length
......
14.1
▼
13.9
▼
• anterior-posterior width
......
1.08
▼
1.00
▼▼
• medial-lateral width
......
1.30
▼
1.20
▼▼
10
strains
age
16wks
Inbred
Chesler3
periosteal (outer) circumference, femoral mid-diaphysis
[mm] ......
age
various
CC pre
bone — strength — femur
biomechanical test
Donahue2
femur biomechanical properties
• displacement curve
......
19.0
▼
18.6
▼
• break point
......
17.7
▼
16.7
▼
• 95% break load
......
11.0
10.8
• displacement
......
0.212
▼
0.235
▼
10
strains
age
16wks
Inbred
bone — strength — femur
bone strength test
Donahue2
femur strength and fragility characteristics
• break point
......
3.51
▼
3.68
▼
• peak load
......
2.72
▼
3.10
▼
• intrinsic stiffness
......
4.99
▲
5.63
▲▲
• extrinsic stiffness
......
127
▼
128
▼
• extrinsic strength (ultimate force)
......
281
268
10
strains
age
16wks
Inbred
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