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blood – clinical chemistry
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bilirubin
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enzymes
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Phenotype data: blood--clinical chemistry enzymes
Measurements:
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blood — clinical chemistry — enzymes — ALP metabolic panel
Eumorphia1
alkaline phosphatase (plasma ALP)
[IU/L]
4
strains
age
12wks
Inbred
RIKEN-EAD1
alkaline phosphatase (plasma ALP)
[IU/L]
35
strains
age
8wks
Inbred
Yuan3
alkaline phosphatase (serum ALP) [IU/L]
6mo
12mo
18mo
• age comparison
31
strains
ages shown
Inbred
Donahue9
alkaline phosphatase (serum ALP)
[IU/L]
25
strains
age
11wks
B6.PWD consomic
RIKEN-EAD2
alkaline phosphatase (plasma ALP)
[IU/L]
26
strains
age
8wks
wild-derived RBRC
Select all these
blood — clinical chemistry — enzymes — ALT metabolic panel
Eumorphia1
alanine aminotransferase (plasma ALT)
[IU/L]
4
strains
age
12wks
Inbred
Harrill2
alanine aminotransferase (serum ALT) [IU/L]
control and
DB289
control
DB289
difference
34
strains
age
6-8wks
Inbred
Jaxpheno3
alanine aminotransferase (plasma ALT) [IU/L]
age 8wks
age 16wks
• age comparison
11
strains
ages shown
Inbred
Paigen1
alanine aminotransferase (plasma ALT)
[IU/L]
high-fat diet
8wks
43
strains
age
15-19wks
Inbred
RIKEN-EAD1
alanine aminotransferase (plasma ALT)
[IU/L]
35
strains
age
8wks
Inbred
Rusyn2
alanine aminotransferase (serum ALT), naive
[IU/L]
17
strains
age
7wks
Inbred
Rusyn2
alanine aminotransferase (serum ALT) [IU/L]
control and
trichloroethylene
control group:
2h
8h
24h
• time comparison
treated group:
2h
8h
24h
• time comparison
17
strains
age
7wks
Inbred
Rusyn5
serum alanine aminotransferase (ALT) [IU/L]
high-fat diet, ethanol
high-fat only
high-fat and ethanol
• comparison
14
strains
age
8-14wks
Inbred
Threadgill1
alanine aminotransferase (serum ALT) [IU/L]
control and
acetaminophen
100 mg/kg:
control
4h
12h
24h
All
• time comparison
37
strains
age
8-17wks
Inbred
Threadgill2
alanine aminotransferase (serum ALT) [IU/L]
acetaminophen
50mg/kg
50 mg/kg
300 mg/kg
• comparison
5
strains
age
6-8wks
Inbred
Yuan3
alanine animotransferase (plasma ALT) [IU/L]
6mo
12mo
18mo
• age comparison
32
strains
ages shown
Inbred
Donahue9
alanine aminotransferase (serum ALT)
[IU/L]
25
strains
age
11wks
B6.PWD consomic
Paigen3
alanine aminotransferase (plasma ALT)
[IU/L]
high-fat diet
8wks
8
strains
age
15-19wks
obesity mutants
RIKEN-EAD2
alanine aminotransferase (plasma ALT)
[IU/L]
26
strains
age
8wks
wild-derived RBRC
Select all these
blood — clinical chemistry — enzymes — AST metabolic panel
Eumorphia1
aspartate aminotransferase (plasma AST; SGOT)
[IU/L]
4
strains
age
12wks
Inbred
RIKEN-EAD1
aspartate aminotransferase (plasma AST)
[IU/L]
35
strains
age
8wks
Inbred
Rusyn2
aspartate aminotransferase (serum AST), naive
[IU/L]
17
strains
age
7wks
Inbred
Rusyn2
aspartate aminotransferase (serum AST) [IU/L]
control and
trichloroethylene
control group:
2h
8h
24h
• time comparison
treated group:
2h
8h
24h
• time comparison
17
strains
age
7wks
Inbred
Threadgill1
aspartate aminotransferase (serum AST) [IU/L]
control and
acetaminophen
control
post-Rx mg/kg:
100
200
300
All
• comparison
37
strains
age
8-17wks
Inbred
Lake1
aspartate aminotransferase (plasma AST)
[mg/dL]
23
strains
age
8wks
B6.A consomic
Donahue9
aspartate aminotransferase (serum AST; SGOT)
[IU/L]
25
strains
age
11wks
B6.PWD consomic
Svenson3
aspartate aminotransferase (plasma AST)
[mg/dL]
21
strains
age
8wks
B6.PWD consomic
RIKEN-EAD2
aspartate aminotransferase (plasma AST)
[IU/L]
26
strains
age
8wks
wild-derived RBRC
Select all these
blood — clinical chemistry — enzymes — misc metabolic panel
Eumorphia1
creatine kinase (plasma CK)
[IU/L]
4
strains
age
12wks
Inbred
Eumorphia1
lactic acid dehydrogenase (plasma LDH)
[IU/L]
4
strains
age
12wks
Inbred
Eumorphia1
plasma alpha-amylase
[IU/L]
4
strains
age
12wks
Inbred
Jaxpheno3
creatine kinase (plasma CK) [IU/L]
age 8wks
age 16wks
• age comparison
11
strains
ages shown
Inbred
RIKEN-EAD1
lactate dehydrogenase (plasma LDH)
[IU/L]
35
strains
age
8wks
Inbred
RIKEN-EAD1
plasma amylase
[U/L]
35
strains
age
8wks
Inbred
Shockley1
glutamate dehydrogenase (GLDH) [IU/L]
control and
high-fat diet
4wks
control diet
high-fat diet
difference
• comparison
10
strains
age
10-13wks
Inbred
Yuan3
lipase (plasma LIP) [U/L]
6mo
12mo
18mo
• age comparison
32
strains
ages shown
Inbred
Donahue9
lipase (serum LIP)
[U/L]
25
strains
age
11wks
B6.PWD consomic
Donahue9
lactate dehydrogenase (serum LDH)
[U/L]
25
strains
age
11wks
B6.PWD consomic
RIKEN-EAD2
lactate dehydrogenase (plasma LDH)
[IU/L]
26
strains
age
8wks
wild-derived RBRC
RIKEN-EAD2
plasma amylase
[U/L]
26
strains
age
8wks
wild-derived RBRC
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