|
kidney — function — urinalysis
ELISA
|
|
|
|
urine kidney injury molecule 1 (KIM-1)
[pg]
| control and
|
DB289
|
|
......
115
(N=3)
......
1111
......
9.66
|
Inbred
|
| |
|
kidney — function — urinalysis
urinalysis
|
|
|
|
Inbred
|
|
|
|
Inbred
|
|
|
|
Inbred
|
|
|
|
urine volume
[mL]
| control and
|
DB289
|
|
......
0.700
......
1.30
......
1.86
|
Inbred
|
|
|
|
creatinine (urine CREA)
[mg/mL]
| control and
|
DB289
|
|
......
0.380
......
0.116
......
0.305
|
Inbred
|
|
|
|
microalbumin (urine MA)
[mg/dL]
|
|
......
0.268
0.463
......
9.13
4.73
......
3.14
0.0850
|
ages shown
Inbred
|
|
|
|
creatinine (urine CREA)
[mg/dL]
|
|
......
67.0
46.7
......
59.2
89.2
......
57.3
70.2
|
ages shown
Inbred
|
|
|
|
albumin-creatinine ratio (urine ACR)
[mg/g]
|
|
......
5.12
13.2
......
143
59.6
......
31.8
1.00
|
ages shown
Inbred
|
|
|
|
CC pre
|
|
|
|
CC pre
|
|
|
|
CC pre
|
| |
|
kidney — morphology — length
metric
|
|
|
......
......
|
CC pre
|
| |
|
kidney — morphology — volume
metric
|
|
|
|
CC pre
|
| |
|
kidney — morphology — weight
scales
|
|
|
weight:
......
226
216
......
106
78.1
......
120
137
normalized:
......
12.3
9.38
......
5.79
3.41
......
6.54
5.93
|
Inbred
|
|
|
|
kidney (left) weight
[g]
| control and
|
DB289
|
|
......
0.112
......
0.102
|
Inbred
|
|
|
|
kidney (right) weight
[g]
| control and
|
DB289
|
|
......
0.116
......
0.104
|
Inbred
|
|
|
|
kidney (both) weight
[g]
| control and
|
DB289
|
|
......
0.228
......
0.206
|
Inbred
|
|
|
|
total kidney weight as percent of body weight
[%]
| control and
|
DB289
|
|
......
1.35
......
1.38
......
1.02
|
Inbred
|
|
|
......
0.103
0.142
......
0.117
0.164
|
ages shown
Inbred
|
|
|
|
kidney (right) weight
[g]
|
|
......
0.159
0.149
......
0.134
0.174
|
ages shown
Inbred
|
|
|
|
kidney (left) weight, as percent of body weight
[%]
|
|
......
0.579
0.585
......
0.535
0.537
|
ages shown
Inbred
|
|
|
|
kidney (right) weight, as percent of body weight
[%]
|
|
......
0.901
0.611
......
0.608
0.570
|
ages shown
Inbred
|
|
|
......
0.394
......
1.27
|
Inbred
|
|
|
|
CC diallel
|
|
|
......
0.206
0.212
(N=2)
......
......
|
CC pre
|
| |
|
kidney — xenobiotics — drug and metabolite concentration
HPLC
|
|
|
|
kidney metabolite (DB75) concentration
[µM]
| control and
|
DB289
|
|
......
1.60
......
1816
|
Inbred
|