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WSB/EiJ strain
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kidney
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Phenotype data: kidney all
Measurements:
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WSB/EiJ
averages
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kidney — function — urinalysis
ELISA
Harrill2
urine kidney injury molecule 1 (KIM-1) [pg]
control and
DB289
• control
......
24.2
(N=4)
• DB289
......
54.0
• difference
......
2.23
34
strains
age
6-8wks
Inbred
kidney — function — urinalysis
spectrophotometry
Rusyn5
urine alcohol concentration (UAC), daily average [mg/dL]
high-fat diet, ethanol
• high-fat only
......
31.3
(N=3)
▲
• high-fat and ethanol
......
146
(N=3)
• comparison
14
strains
age
8-14wks
Inbred
Rusyn5
urine alcohol concentration (UAC), daily peak [mg/dL]
high-fat diet, ethanol
• high-fat only
......
95.1
(N=3)
• high-fat and ethanol
......
395
(N=3)
• comparison
14
strains
age
8-14wks
Inbred
kidney — function — urinalysis
urinalysis
Harrill2
urine volume [mL]
control and
DB289
• control
......
0.600
▼
• DB289
......
0.400
▼
• difference
......
0.667
34
strains
age
6-8wks
Inbred
Harrill2
creatinine (urine CREA) [mg/mL]
control and
DB289
• control
......
• DB289
......
• difference
......
34
strains
age
6-8wks
Inbred
Korstanje1
microalbumin (urine MA) [mg/dL]
• 12mo
......
3.39
7.17
▲
• 18mo
......
4.92
10.7
• 24mo
......
27.3
▲
60.7
▲▲
• age comparison
30
strains
ages shown
Inbred
Korstanje1
creatinine (urine CREA) [mg/dL]
• 12mo
......
104
▲
108
▲
• 18mo
......
116
▲
66.7
• 24mo
......
75.7
94.1
▲
• age comparison
30
strains
ages shown
Inbred
Korstanje1
albumin-creatinine ratio (urine ACR) [mg/g]
• 12mo
......
34.4
67.9
• 18mo
......
42.8
160
• 24mo
......
407
703
▲▲
• age comparison
30
strains
ages shown
Inbred
kidney — morphology — length
metric
Chesler3
kidney length [cm]
• left
......
• right
......
• comparison
age
various
CC pre
kidney — morphology — volume
metric
Chesler3
kidney volume
[cm
3
] ......
age
various
CC pre
kidney — morphology — weight
scales
Harrill2
kidney (left) weight [g]
control and
DB289
• control
......
0.105
(N=4)
• DB289
......
0.0780
▼
• comparison
34
strains
age
6-8wks
Inbred
Harrill2
kidney (right) weight [g]
control and
DB289
• control
......
0.117
(N=4)
• DB289
......
0.0840
▼
• comparison
34
strains
age
6-8wks
Inbred
Harrill2
kidney (both) weight [g]
control and
DB289
• control
......
0.222
(N=4)
• DB289
......
0.160
▼
• comparison
34
strains
age
6-8wks
Inbred
Harrill2
total kidney weight as percent of body weight [%]
control and
DB289
• control
......
1.93
(N=4)
▲▲
• DB289
......
1.72
▲
• difference
......
0.891
34
strains
age
6-8wks
Inbred
Chesler2
kidney (left) weight
[g] ......
0.147
62
strains
age
various
CC diallel
Chesler3
kidney weight [g]
• left
......
0.147
• right
......
• both
......
• comparison
age
various
CC pre
kidney — xenobiotics — drug and metabolite concentration
HPLC
Harrill2
kidney metabolite (DB75) concentration [µM]
control and
DB289
• control
......
• DB289
......
1176
• comparison
34
strains
age
6-8wks
Inbred
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