|
kidney — function — urinalysis
ELISA
|
|
|
|
urine kidney injury molecule 1 (KIM-1)
[pg]
| control and
|
DB289
|
|
......
51.0
(N=4)
......
86.3
(N=3)
......
1.69
|
Inbred
|
| |
|
kidney — function — urinalysis
urinalysis
|
|
|
|
Inbred
|
|
|
|
Inbred
|
|
|
|
Inbred
|
|
|
|
urine volume
[mL]
| control and
|
DB289
|
|
......
0.740
......
0.500
(N=4)
......
0.676
|
Inbred
|
|
|
|
creatinine (urine CREA)
[mg/mL]
| control and
|
DB289
|
|
......
0.256
......
0.253
(N=3)
......
0.988
|
Inbred
|
|
|
|
microalbumin (urine MA)
[mg/dL]
|
|
......
1.38
0.668
......
8.87
0.136
......
7.83
5.58
|
ages shown
Inbred
|
|
|
|
creatinine (urine CREA)
[mg/dL]
|
|
......
30.3
42.1
......
35.9
51.0
......
25.7
34.2
|
ages shown
Inbred
|
|
|
|
albumin-creatinine ratio (urine ACR)
[mg/g]
|
|
......
44.4
16.5
......
201
3.00
......
176
138
|
ages shown
Inbred
|
| |
|
kidney — morphology — weight
scales
|
|
|
|
kidney (left) weight
[g]
| control and
|
DB289
|
|
......
0.164
......
0.105
(N=4)
|
Inbred
|
|
|
|
kidney (right) weight
[g]
| control and
|
DB289
|
|
......
0.136
......
0.107
(N=4)
|
Inbred
|
|
|
|
kidney (both) weight
[g]
| control and
|
DB289
|
|
......
0.300
......
0.212
(N=4)
|
Inbred
|
|
|
|
total kidney weight as percent of body weight
[%]
| control and
|
DB289
|
|
......
1.82
......
1.46
(N=4)
......
0.802
|
Inbred
|
|
|
......
0.460
......
1.74
|
Inbred
|
| |
|
kidney — xenobiotics — drug and metabolite concentration
HPLC
|
|
|
|
kidney metabolite (DB75) concentration
[µM]
| control and
|
DB289
|
|
......
......
916
(N=4)
|
Inbred
|