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Phenotype data: cell and tissue damage all
Phenotype data > SM/J strain >
cell and tissue damage
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apoptosis
chromosome instability
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cell and tissue damage — apoptosis         flow cytometry  
Mills1
early apoptotic splenocytes [%]  
      • 6mo  ...... 7.47 (N=3)   4.20 (N=3)  
      • 12mo  ...... 4.50 (N=3)   3.17 (N=3)  
      • 20mo  ...... 5.00 (N=3)   9.90 (N=2) ▲▲  
        • age comparison  
30 strains   ages shown
  Inbred
Mills1
late apoptotic splenocytes [%]  
      • 6mo  ...... 8.97 (N=3)   6.73 (N=3)  
      • 12mo  ...... 5.33 (N=3)   6.23 (N=3)  
      • 20mo  ...... 5.47 (N=3)   8.55 (N=2) ▲▲  
        • age comparison  
30 strains   ages shown
  Inbred
Mills1
all apoptotic splenocytes [%]  
      • 6mo  ...... 16.4 (N=3)   10.9 (N=3)  
      • 12mo  ...... 9.83 (N=3)   9.40 (N=3)  
      • 20mo  ...... 10.5 (N=3)   18.4 (N=2) ▲▲  
        • age comparison  
30 strains   ages shown
  Inbred
Mills1
apoptosis profiles (early, late, all)  
      6mo 
      12mo 
      20mo 
     
30 strains   ages shown
  Inbred
 
cell and tissue damage — chromosome instability         flow cytometry  
Mills1
reticulocytes with micronuclei [%]  
      • 6mo  ...... 0.0303   0.0187  
      • 12mo  ...... 0.0167   0.0743 (N=3)  
      • 20mo  ...... 0.115 ▲▲   0.0342  
        • age comparison  
30 strains   ages shown
  Inbred
Mills1
red blood cells (RBC) with micronuclei [%]  
      • 6mo  ...... 0.0810   0.255  
      • 12mo  ...... 0.0872   0.287 (N=3)  
      • 20mo  ...... 0.104   0.114  
        • age comparison  
30 strains   ages shown
  Inbred
Mills1
non-nucleated peripheral blood cells with micronuclei [%]  
      • 6mo  ...... 0.118   0.258  
      • 12mo  ...... 0.107   0.323 (N=3)  
      • 20mo  ...... 0.142   0.150  
        • age comparison  
30 strains   ages shown
  Inbred
Mills1
chromosome instability profiles (retic, RBC, all)  
      6mo 
      12mo 
      20mo 
     
30 strains   ages shown
  Inbred


 


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