Home       About             Help       Phenotype data > SJL/J strain > blood – xenobiotics Options: alcohol concentration drug and metabolite concentration all Focus: all Measurements: About these SJL/J averages (♀ ♂) Exit SJL/J mode blood — xenobiotics — alcohol concentration         gas chromatography   Crabbe4 blood ethanol concentration (BEC), 35 min post-injection, dowel (15.8 mm) test   [mg/mL] ......   ethanol   2g/kg i.p. 8 strains   age 12-16wks   Inbred Crabbe4 blood ethanol levels following grip strength test at various times after treatment [mg/mL]   ethanol   2g/kg i.p.       time after ethanol:             • 30min  ...... 1.17 ▼   1.70               • 60min  ...... 1.34   1.56 (N=4)               • 105min  ...... 1.03   1.35 (N=4)               • 150min  ...... 0.462   0.865 (N=4)                 • time comparison   21 strains   age 7-12wks   Inbred   blood — xenobiotics — drug and metabolite concentration         HPLC   Wiltshire2 drug and metabolite concentration [ng/mL]   fluoxetine         • fluoxetine  ...... 1275         • norfluoxetine  ...... 1124           • comparison   30 strains   age 10-11wks   Inbred   blood — xenobiotics — drug and metabolite concentration         mass spectrometry   Crowley1 plasma haloperidol concentration [nM]   haloperidol       day:             • 30  ...... 26.1               • 60  ...... 22.7               • 90  ...... 12.4 (N=4)               • 120  ...... 7.45 (N=4)                 • time comparison   27 strains   age 9-28wks   Inbred

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