Home       About             Help       Phenotype data > PWD/PhJ strain > blood – xenobiotics Options: alcohol concentration drug and metabolite concentration all Focus: all Measurements: About these PWD/PhJ averages (♀ ♂) Exit PWD/PhJ mode blood — xenobiotics — alcohol concentration         spectrophotometry   Rusyn5 blood alcohol concentration (BAC) [mg/dL]   high-fat diet, ethanol       • high-fat only  ...... 37.7 (N=3)         • high-fat and ethanol  ...... 241 (N=3)           • comparison   14 strains   age 8-14wks   Inbred   blood — xenobiotics — drug and metabolite concentration         HPLC   Rusyn2 dichloroacetic acid (serum DCA x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ...... 105 (N=2) ▲               • 8h  ...... 220 (N=2)               • 24h  ...... 0 (N=3)                 • time comparison   17 strains   age 7wks   Inbred Rusyn2 trichloroacetic acid (serum TCA) [nmol/mL]   trichloroethylene         treated group:             • 2h  ...... 397 (N=2) ▲▲               • 8h  ...... 623 (N=2)               • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 DCV cysteine (serum DCVC x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ...... 0.760 (N=1)               • 8h  ......             • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 DCV glutathione (serum DCVG x 10-3) [nmol/mL]   trichloroethylene         treated group:             • 2h  ...... 1.62 (N=2)               • 8h  ......             • 24h  ......               • time comparison   17 strains   age 7wks   Inbred Rusyn2 above metabolites compared   trichloroethylene         treated group:             2h              8h              24h              17 strains   age 7wks   Inbred

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