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Phenotype data: blood--xenobiotics all
Phenotype data >
blood – xenobiotics
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alcohol concentration
drug and metabolite concentration
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  clinical chemistry
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blood — xenobiotics — alcohol concentration         gas chromatography  
Crabbe4
blood ethanol concentration (BEC), 35 min post-injection, dowel (15.8 mm) test   [mg/mL]   ethanol   2g/kg i.p.
8 strains   age 12-16wks
  Inbred
Crabbe4
blood ethanol levels following grip strength test at various times after treatment [mg/mL]   ethanol   2g/kg i.p.
      time after ethanol:    • 30min  • 60min  • 105min  • 150min    • time comparison  
21 strains   age 7-12wks
  Inbred
 
blood — xenobiotics — alcohol concentration         spectrophotometry  
Rusyn5
blood alcohol concentration (BAC) [mg/dL]   high-fat diet, ethanol
      • high-fat only  • high-fat and ethanol    • comparison  
14 strains   age 8-14wks
  Inbred
Bennett3
blood ethanol concentration (BEC) [mg/mL]   ethanol  
      • first loss of balance (ataxia)  • first regain of balance  • second regain of balance    • comparison  
72 strains   age 8-14wks
  ILSXISS
Bennett3
acute functional tolerance to two-stage injections of EtOH [mg/mL]   ethanol  
      • as a function of first regain of balance  • as a function of first loss of balance    • comparison  
72 strains   age 8-14wks
  ILSXISS
 
blood — xenobiotics — drug and metabolite concentration         flame photometry  
Gould1
serum lithium concentration [mmol/L]   lithium
      lithium dose [mg/kg]: • 200  • 300  • 400    • comparison  
11 strains   age 7-8wks
  Inbred
 
blood — xenobiotics — drug and metabolite concentration         HPLC  
Rusyn2
dichloroacetic acid (serum DCA x 10-3) [nmol/mL]   trichloroethylene  
      treated group:  • 2h  • 8h  • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
trichloroacetic acid (serum TCA) [nmol/mL]   trichloroethylene  
      treated group:  • 2h  • 8h  • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
DCV cysteine (serum DCVC x 10-3) [nmol/mL]   trichloroethylene  
      treated group:  • 2h  • 8h  • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
DCV glutathione (serum DCVG x 10-3) [nmol/mL]   trichloroethylene  
      treated group:  • 2h  • 8h  • 24h    • time comparison  
17 strains   age 7wks
  Inbred
Rusyn2
above metabolites compared   trichloroethylene  
      treated group:  2h  8h  24h 
17 strains   age 7wks
  Inbred
Threadgill2
serum acetominophen (APAP) [µg/mL]     baseline and  acetaminophen 50mg/kg
      • baseline  • 0.5h  • 1h  • 2h  • 3h  • 6h    • time comparison  
5 strains   age 6-8wks
  Inbred
Threadgill2
serum acetaminophen sulfate (APAP-sulfate) [µg/mL]     baseline and  acetaminophen 50mg/kg
      • baseline  • 0.5h  • 1h  • 2h  • 3h  • 6h    • time comparison  
5 strains   age 6-8wks
  Inbred
Threadgill2
serum acetaminophen glucuronide (APAP-Glc) [µg/mL]     baseline and  acetaminophen 50mg/kg
      • baseline  • 0.5h  • 1h  • 2h  • 3h  • 6h    • time comparison  
5 strains   age 6-8wks
  Inbred
Threadgill2
serum acetominophen (APAP) [µg/mL]     baseline and  acetaminophen 300mg/kg
      • baseline  • 0.5h  • 1h  • 2h  • 3h  • 6h    • time comparison  
5 strains   age 6-8wks
  Inbred
Threadgill2
serum acetaminophen sulfate (APAP-sulfate) [µg/mL]     baseline and  acetaminophen 300mg/kg
      • baseline  • 0.5h  • 1h  • 2h  • 3h  • 6h    • time comparison  
5 strains   age 6-8wks
  Inbred
Threadgill2
serum acetaminophen glucuronide (APAP-Glc) [µg/mL]     baseline and  acetaminophen 300mg/kg
      • baseline  • 0.5h  • 1h  • 2h  • 3h  • 6h    • time comparison  
5 strains   age 6-8wks
  Inbred
Wiltshire2
drug and metabolite concentration [ng/mL]   fluoxetine  
      • fluoxetine  • norfluoxetine    • comparison  
30 strains   age 10-11wks
  Inbred
 
blood — xenobiotics — drug and metabolite concentration         mass spectrometry  
Crowley1
plasma haloperidol concentration [nM]   haloperidol
      day: • 30  • 60  • 90  • 120    • time comparison  
27 strains   age 9-28wks
  Inbred
Gould2
plasma nicotine [ng/mL]   nicotine
      • acute 0.09mg dose  • chronic 6.3mg dose    • comparison  
8 strains   age 8-12wks
  Inbred
Gould2
plasma cotinine [ng/mL]   nicotine
      • acute 0.09mg dose  • chronic 6.3mg dose    • comparison  
8 strains   age 8-12wks
  Inbred
Gould2
compare nicotine vs. cotinine  
      acute 0.09mg dose  chronic 6.3mg dose 
8 strains   age 8-12wks
  Inbred


 


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